Lynch Syndrome -

Lynch Syndrome

Molecular Mechanism and Current Clinical Practice

Naohiro Tomita (Herausgeber)

Buch | Softcover
143 Seiten
2021 | 1st ed. 2020
Springer Verlag, Singapore
978-981-15-6893-0 (ISBN)
90,94 inkl. MwSt
This book offers a comprehensive review of Lynch Syndrome (LS), addressing both the basic and clinical aspects of this condition.



Due to the recent advances in our understanding of the genetic mechanism of LS, and to new screening methods, including universal screening and/or multi-gene panel analysis, the standard treatment strategy for patients and family members of LS have been steadily improving. In this book, experts describe the disease’s manifestations, discuss state-of-the-art diagnosis and management options, and offer a cutting-edge overview of the genetic and epigenetic basis of the syndrome.



Providing essential insights into this new phase in the management of LS, this book is a valuable resource not only for colorectal surgeons, but also for general gastrointestinal clinicians, gynecologists, oncologists and all basic researchers with an interest in LS.

Naohiro Tomita Professor Emeritus, Division of Lower GI Surgery, Department of Surgery, Hyogo College of Medicine Nishinomiya, Hyogo, Japan   Specially Appointed Adviser, Cancer Treatment Center, Toyonaka Municipal Hospital Toyonaka, Osaka, Japan ntomita@hyo-med.ac.jp  

1 Molecular mechanism of Lynch syndrome.- 2 Clinical features of Lynch syndrome.- 3 Pathology of Lynch syndrome-associated tumors.- 4 Immunohistochemistry for mismatch repair proteins.- 5 Genetic analysis for Lynch syndrome.- 6 Lynch syndrome-associated gynecological malignancies​.- 7 Lynch syndrome-associated urological malignancies.- 8 Screening for Lynch syndrome.- 9 Surveillance Colonoscopy for Lynch Syndrome Patients.- 10 Surgical approach for colorectal cancer in patients with Lynch syndrome.- 11 Immunotherapy for Lynch syndrome patients.- 12 Chemoprevention for Lynch syndrome-associated malignancies.- 13 International collaboration for Lynch syndrome.

Erscheinungsdatum
Zusatzinfo 27 Illustrations, color; IX, 143 p. 27 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizinische Fachgebiete Chirurgie Viszeralchirurgie
Medizinische Fachgebiete Innere Medizin Gastroenterologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Schlagworte Colorectal Cancer • colorectal neoplasms • Gynecological Malignancies • Multiple-gene panel analysis • Urological Malignancies
ISBN-10 981-15-6893-6 / 9811568936
ISBN-13 978-981-15-6893-0 / 9789811568930
Zustand Neuware
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