Atopic Dermatitis: Inside Out or Outside In

Dr. Vivian Shi is the Director of Clinical Trials and the Eczema Specialty Clinic at the University of Arkansas for Medical Sciences. Her research and clinical interests are in complex inflammatory skin conditions, skin barrier repair, transepidermal drug delivery, and integrative dermatology. She was an integral part of the team of researchers characterizing the pathophysiology of atopic dermatitis using a transgenic interleukin-4 mouse model of atopic dermatitis. She has published over 150 peer-reviewed articles, and is on the speaker's bureau and the steering committee for the U.S. National Eczema Association and is a faculty member of the International Eczema Council. She has served as the principal investigator for numerous industry-sponsored and investigator-initiated clinical and translational studies in eczematous conditions. She regularly speaks in national and international conferences on atopic dermatitis and inflammatory skin conditions. Additionally, she is the recipient of the several prestigious awards and grants.

Section I: A History of Atopy 1 Historic Perspective 2 Atopy Redefined 3 Atopy of the Skin 4 Epidemiology

Section II: External Factors 5 Skin Barrier 6 Skin and Gut Microbiome 7 Immunogens 8 Nutrition 9 Oxidative Stress, Environmental factors, Pollutants 10 Clinical Evidence: External Factors

Section III: Internal  Factors 11 Keratinocytes 12 Microvasculature 13 Humoral Factors 14 Cellular Factors 15 Skin-Gut-Lung Epithelial Permeability 16 Neurosensory Mechanisms 17 Epigenetics 18 Clinical Evidence: Internal Factors

Section IV: Clinician's Corner 19 Therapeutic Guideline Overview 20 Topical Therapies 21 Wound care 22 Skin barrier Repair 23 Emerging Targeted Treatments 24 Microbiome Modulation 25 Itch and Pain Treatments 26 Complementary and Alternative Approaches 1 27 Complementary and Alternative Approaches 2