Osteoporotic Fracture and Systemic Skeletal Disorders

Hideaki E. Takahashi, MD, PhDProfessor Emeritus, Niigata UniversityFormer Chair, Orthopaedic Department Niigata UniversityPresident Emeritus, Niigata University of Health and WelfareConsultant, Niigata Bone Science Institute David B. Burr, PhD, FAAADistinguished Professor, Indiana UniversityAssociate Vice Chancellor for Research, IUPUI Dept. of Anatomy and Cell BiologyDept. of Biomedical EngineeringIndiana University School of Medicine Noriaki Yamamoto, MD, PhD Director, Niigata Rehabilitation HospitalHead, Orthopaedic Department, Niigata Rehabilitation HospitalDirector, Niigata Bone Science InstituteSecretary General, NPO Fragility Fracture Network-Japan

​Part I　Bone Morphometry, and Radiological Assessment.- 1. Past, Present and Future of Bone Histomorphometry .- 2. Effects of aging on bone fragility.-3. Cellular and molecular biology in bone remodeling.- 4. Modeling and Modeling-based bone formation in trabecular packets.- 5. A role of canopy and reversal cells in bone remodeling.- 6. Significance of reversal-resorption phase in cortical porosity.- 7. A role of focal osteoporosis defects in hip fracture.- 8. Bone Tissue and its mechanical regulation.- 9. Minimodeling, modeling-based formation, in human trabeculae and bone.- 10.　Fracture healing and cause of non-union.- 11. Disturbance of osteonal remodeling in atypical femoral fracture.- 12. Microcrack and microdamage.- 13. 3D microstructure of bone tissue 14. 3D bone morphometry.- 15. DXA and SQ assessment of osteoporosis.- 16. Assessment of osteoporosis by HR-pQCT, QCT, MRI.- 17.　FRAX  (John A. Kanis).- Part II Metabolic and Systemic Disorders and Bone.- 18. Skeletal disorders on Hypovitamin D.- 19.　Diabetes and bone.- 20.　CKD-MBD.- 21. Ehlers-Danlos Syndrome, IgG4 related disorders and Hepatitis type C.- Part III　Medical and Conservative Treatment.- 22. Effects of Osteoporosis Drugs – BMD and Morphological Assessment.-23. Vibration as an exercise modality to prevent sarcopenia.- Part IV Operative Treatment.- 24. Operative treatment of hip fracture.- 25. Balloon Kyphoplasty.- 26. Operative treatment of spinal disorders with consideration of dynamic axis of spinal column and lower extremities.- 27. Operative treatment of spinal disorders with minimum invasive technique.