Integrated Omics Approaches to Infectious Diseases (eBook)

This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

Dr. Saif Hameed is currently an Associate Professor at Amity Institute of Biotechnology, Amity University, Haryana. Dr. Hameed did his Bachelor's from the University of Delhi and Masters from Jamia Hamdard and completed his doctoral studies in Life Sciences from Jawaharlal Nehru University. He also worked as a visiting scholar in Institute für Mikrobiologie, Heinrich-Heine-Universität, Düsseldorf, Germany, in 2008. Dr. Hameed has received the Young Scientist award from the Science and Engineering Research Board, Department of Science and Technology, New Delhi. Dr. Hameed is actively engaged in research in infectious diseases particularly multidrug resistance (MDR) in pathogenic fungi. He has around 50 peer-reviewed papers to his credit in high repute journals, 3 books, 21 book chapters, and 25 popular articles, with 2 of them as 'cover story' and guided 4 doctoral students. He is a life member of the Association of Microbiologists of India (AMI) and the International Society for Infectious Diseases (ISID).

Dr. Zeeshan Fatima is currently working as Associate Professor at Amity Institute of Biotechnology, Amity University, Haryana. Dr. Fatima did her Bachelor's and Masters from Banaras Hindu University and earned her doctoral degree in Biochemistry from Aligarh Muslim University. She has held research positions under nationally and internationally funded research projects, including her Research Associateship at BHU and JNU and postdoctoral training from the University of Cincinnati, Ohio, USA. Dr. Fatima has received two Young Scientist awards under Fast Track and Women Scientist Schemes, respectively, from the Science and Engineering Research Board, Department of Science and Technology, New Delhi. She is actively engaged in infectious diseases research, particularly on multidrug resistance in human pathogens, Mycobacterium tuberculosis and Candida albicans. She has 3 books and around 45 peer-reviewed papers to her credit in journals of high repute and supervised 4 doctoral thesis. She is a life member of the Association of Microbiologists of India (AMI), Society of Biological Chemists (SBC), India and the International Society for Infectious Diseases (ISID).

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This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.