Peptides and Non Peptides of Oncologic and Neuroendocrine Relevance
Springer Verlag
978-88-470-0295-1 (ISBN)
Describes the ability of a series of endocrine-derived compounds, i.e. CHRH, LHRH, somatostatin, anti-androgens, and aromatase inhibitors to exert a direct anti-neoplastic activity or to potentiate the activity of traditional chemotherapeutic agents on neuroendocrine and solid tumors. In addition, a new class of potent GH-releasers, GSHs/Ghrelin, endowed with important endocrine and extra-endcocrine action, is presented. Therefore, in addition to traditional chemotherapy, characterized by high toxicity and non-selective action on tumoral cells, the reader can find a new approach with more selective, less cytotoxic endocrine derived compounds.
LHRH/Somatostatin.- Chapter1 Twenty-five Years of Endocrine Oncology with Analogs of Hypothalamic Peptides: an Overview.- Chapter2 Analogs of Luteinizing Hormone-releasing Hormone in Benign Prostatic Hyperplasia and Advanced Renal Cell Carcinoma.- Chapter3 Luteinizing Hormone-releasing Hormone Antagonists in Gynecology.- Chapter4 Physiology and Pharmacology of Somatostatin and Its Receptors.- Chapter5 Investigation of LHRH Receptor Involvement in Melanoma Growth and Progression.- Somatostatin/GHRH/GH.- Chapter6 Cortistatin: Not Simply a Natural Somatostatin Analogue.- Chapter7 Antineoplastic and Antiangiogenic Actions of Somatostatin Analogs.- Chapter8 Somatostatin in Clinical Endocrinology.- Chapter9 Antagonists of Growth Hormone-releasing Hormone in Oncology.- Chapter10 GH Receptor Antagonists: Basic Knowledge and Clinical Perspectives.- Ghrelin and Ghrelin Mimetics (GHS).- Chapter11 Hypothalamic Circuits Responsive to Ghrelin: Regulation by Leptin and Insulin.- Chapter12 Physiological Function of Growth Hormone Secretagogue Receptors in the Cardiovascular System.- Chapter13 Endocrine and Extraendocrine Activity of Ghrelin and the GHS: Basic Research.- Chapter14 Endocrine and Nonendocrine Actions of Ghrelin and GHS: State of the Art in Clinical Research.- Hormonal Treatments for Endocrine-Dependent Tumors.- Chapter15 Hormonal Treatments of Endocrine-Dependent Tumors: Preclinical Aspects.- Chapter16 Hormonal Treatment of Endocrine-Dependent Tumors: Clinical Considerations.- Chapter17 Letrozole in the Treatment of Advanced Breast Cancer.
| Erscheint lt. Verlag | 18.9.2003 |
|---|---|
| Zusatzinfo | XII, 197 p. |
| Verlagsort | Milan |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
| ISBN-10 | 88-470-0295-8 / 8847002958 |
| ISBN-13 | 978-88-470-0295-1 / 9788847002951 |
| Zustand | Neuware |
| Haben Sie eine Frage zum Produkt? |
aus dem Bereich
