HIV Reservoirs

Jurkat-derived (J-Lat, J1.1 and Jurkat E4) and CEM-derived T cell lines (8E5, ACH-2) as Models of Reversible Proviral Latency.- U1 and OM10.1. Myeloid Cell Lines as Surrogate Models Of Reversible Proviral Latency.- An In Vitro System to Model the Establishment and Reactivation of HIV-1 Latencyin primary human CD4+ T cells.- The cultured TCM model of HIV latency.- A Reliable Primary Cell Model for HIV latency: The QUECEL (Quiescent Effector Cell Latency) Method.- TGF-b signaling supports HIV latency in a Memory CD4+ T cell based in vitro model.p Flow Cytometry Sorting of Memory CCR6+CD4+ T-Cells for HIV Reservoirs Quantification.- Human monocyte-derived macrophages (MDM) - Model 1 (GM-CSF).- Human monocyte-derived macrophages (MDM) - Model 2.- Modeling HIV latency in astrocytes with the human neural progenitor cell line HNSC.100.- Hematopoietic stem and progenitor cells (HSPCs).- HIV reservoirs: Modeling, Quantification and Approaches to a Cure.- More than a gender issue: Testis as a distinctive HIV reservoir and its implication for viral eradication.- Experimental Models to Study HIV Latency Reversal from Male Genital Myeloid Cells.- Decidua basalis: An ex vivo Model to Study HIV-1 Infection during Pregnancy and Beyond.- HIV Reservoirs: Modeling, Quantification, and Approaches to a Cure.- Human Hematopoietic Stem Cell (HSC)-Engrafted NSG Mice for HIV Latency Research.- Inducing long-term HIV-1 latency in the TKO-BLT mouse model.- In situ multiplexing to identify, quantify, and phenotype the HIV-1/SIV reservoir within lymphoid tissue.- Single-cell multiparametric analysis of rare HIV-infected cells identified by duplexed RNAflow-FISH.- Ex vivo differentiation of resting CD4+ T lymphocytes enhances detection of replication competent HIV-1 in viral outgrowth assays.- Quantitative Viral Outgrowth Assay to Measure the functional SIV Reservoir in Myeloid Cells.- Near-full-length single-genome HIV-1 DNA sequencing.- TILDA: Tat/rev Induced Limiting Dilution Assay.- Latency Reversal and Clearance of Persistent HIV Infection.- Cure and long-term remission strategies.- Pathways Toward a Functional HIV-1 Cure: Balancing Promise and Perils for CRISPR Therapy.