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Medical Management of Chronic Myelogenous Leukemia

Buch | Hardcover
464 Seiten
1998
Crc Press Inc (Verlag)
978-0-8247-9901-4 (ISBN)
153,35 inkl. MwSt
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Provides a summary of therapies for chronic myelogenous leukemia (CML), discussing both basic pathophysiology and experimental strategies. Containing references, tables, drawings, and photographs, this work is suitable for clinical oncologists, hematologists, immunologists and researchers, amongst others.
This valuable reference provides a timely summary of current therapies for chronic myelogenous leukemia (CML), discussing both basic pathophysiology and new experimental strategies.
Combining the insights of over 30 prominent researchers in the field, Medical Management of Chronic Myelogenous Leukemia
compares interferon therapy with conventional chemotherapy

covers chronic, accelerated, and Philadelphia-negative phases

details standard therapy with IFN- regimens and allogenic stem cell transplantation

describes the utility and limitations of CML animal models

profiles clinical trials testing IFN in combination with other agents

assesses improvements in survival times among CML patients

reviews the effectiveness of Southern blot monitoring

traces the development of oligonucleotides as potential therapeutic agents

outlines therapy with monoclonal antibodies, targeted NK cells, and immune T cells

and more!
Containing over 1500 references, tables, drawings, and photographs, Medical Management of Chronic Myelogenous Leukemia is suitable for clinical oncologists, hematologists, immunologists and researchers in the fields of tumor immunology and cancer immunotherapy, internists, and residents, fellows, and medical school students in these disciplines.

CML Introduction

Chronic Myelogenous Leukemia-A Brief Review, Hagop M. Kantarjian and Moshe Talpaz
Chronic Myelomonocytic Leukemia, John F. Seymour and Jorge E. Cortes
Animal Models of Chronic Myelogenous Leukemia, Richard A. Van Etten
Natural History and Prognostic Factors in Chronic Myelogenous Leukemia: Past, Present, and Future, Sergio Giralt

Chemotherapy and Interferons

Changing Nature of Conventional Therapy in Chronic Myelogenous Leukemia, Rüdiger Hehlmann and Andreas Hochhaus
Interferon Therapy: Is It the Standard of Care?, Sante Tura and Michele Baccarani
Practical Management of Interferon Therapy and Side Effects, Susan O'Brien, Hagop M. Kantarjian, and Moshe Talpaz
Treatment of Chronic Myelogenous Leukemia by Interferon and Cyarabine, François Guilhot
Chronic Myeloid Leukemia: Australian Experience with Interferon Combinations and High-Dose Interferon, Christopher K. Arthur

Bone Marrow Transplantation

Allografting for Chronic Myelogenous Leukemia, David G. Savage and John Michael Goldman
Treatment Algorithm in CML: Bone Marrow Transplantation as Frontline Therapy, Reginald A. Clift
Autologous Stem Cell Transplantation for Chronic Myeloid Leukemia, J. Reiffers, F. X. Mahon, J. M. Boiron, H. Chahine, C. Faberes, T. Cousin, P. Cony-Makhoul, A. Pigneux, A. Agape, A. Broustet, and G. Marit
Philadelphia Chromosome-Negative Chronic Myelogenous Leukemia, Jorge E. Cortes and John Seymour

Monitoring Therapy and Minimal Residual Disease

Monitoring Changes in the Breakpoint Cluster Region During Therapy for CML: The M.D. Anderson Cancer Center Experience, Claire F. Verschraegen
Monitoring the Course of Myelogenous Leukemia by Fluorescence In Situ Hybridization, Chu-Myong Seong, Hagop M. Kantarjian, Moshe Talpaz, Richard Champlin,and Michael Siciliano
Molecular Monitoring of CML During Interferon Treatment: Insights from the Cancer and Leukemia Group B Experience, Wendy Stock

Developmental Therapies

Oligonucleotide Therapeutics for Chronic Myelogenous Leukemia, Alan M. Gewirtz
Role of Cytokines and Adhesion Molecules in Chronic Myelogenous Leukemia, Luis Fayad and Zeev Estrov
ABL Protein Tyrosine Kinase Inhibitors: Potential Clinical Role in CML, Brian J. Druker
Immunotherapy of Chronic Myelogenous Leukemia, David A. Scheinberg, Monica Bocchia, and Richard O'Reilly

Reihe/Serie Basic and Clinical Oncology
Verlagsort Bosa Roca
Sprache englisch
Maße 216 x 279 mm
Gewicht 726 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
ISBN-10 0-8247-9901-1 / 0824799011
ISBN-13 978-0-8247-9901-4 / 9780824799014
Zustand Neuware
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