Handbook of Pediatric Transfusion Medicine

Christopher D. Hillyer, MD, is President and CEO of New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY. Previously, he was the tenured, endowed Distinguished Service Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine and served as director of the Emory Center for Transfusion and Cellular Therapies with responsibility for all aspects of clinical and academic transfusion medicine at Emory’s seven principle hospitals. Dr. Hillyer is an editor of twelve textbooks in transfusion medicine, author of over 160 articles pertaining to transfusion, human immunodeficiency virus, and herpes viruses, most notably cytomegalovirus. Nationally recognized as an expert in hematology and blood transfusion, Dr. Hillyer is also a past-president, board of directors of AABB and a former trustee of the National Blood Foundation. Dr. Hillyer has been awarded many million dollars in research funding from the National Institutes of Health, the Centers for Disease Control and Prevention and other agencies. He was an associate editor of Transfusion and serves on several other editorial boards. Dr. Hillyer was formally recognized for his work in Africa as part of the AABB/Emory cooperative agreement from the President’s Emergency Plan For AIDS Relief (PEPFAR), and is a recipient of two Tiffany Awards from the American Red Cross where he also served as a medical director and a member of their national Medical Advisory Board. He also received the 2014 Emily Cooley Award from AABB for his “significant commitment and contributions to the field of transfusion medicine through extensive teaching, mentoring and professional leadership, and the countless clinical, scientific and innovative resource materials he has created to educate others”. He is a co-founder of Transfusion & Transplantation Technologies, Inc (3Ti) and holds over 20 patents or patents pending. Dr. Hillyer is board certified in transfusion medicine, hematology, medical oncology and internal medicine. He received his BS from Trinity College, and his MD from the University of Rochester School of Medicine, with postgraduate training and fellowships in hematology-oncology, transfusion medicine and bone marrow transplantation at Tufts-New England Medical Center.

Blood Donation
Component Preparation and Storage
Blood Components
Red Blood Cell Antigens and
Human Blood Groups
Pretransfusion Compatibility Testing
Serologic Investigation of Unexpected Antibodies
Leukoreduced Products: Prevention of Leukocyte-Related Transfusion-Associated Adverse Effects
Preparation of Blood Components to Reduce Cytomegalovirus and Other Infectious Risks
Irradiated Products
Washed and/or Volume-Reduced Blood Components
Technical Considerations/Mechanical Devices
Red Blood Cell Transfusions in the Neonate, Infant, Child, and Adolescent
Transfusion of the Pediatric Surgery, Trauma, and Intensive Care Unit Patient
Pediatric Transfusion in Developing Countries
Exchange Transfusion in the Infant
Granulocyte Transfusions in the Neonate and Child
Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass
Hemolytic Disease of the Newborn
Hemoglobinopathies
The Bleeding Child: Congenital and Acquired Disorders
Transfusion of the Patient with Autoimmune Hemolysis
Platelet Transfusions in the Infant and Child
Bone Marrow–Derived Stem Cells
Peripheral Blood Stem Cells
Umbilical Cord Blood Stem Cells
Transfusion Reactions
Noninfectious Complications of Pediatric Transfusion
Infectious Complications
Therapeutic Apheresis
Therapeutic Cytapheresis
Therapeutic Plasma Exchange: Rationales and Indications
Appendix Transfusion Formulas