Coronary Artery Disease: Therapeutics and Drug Discovery -

Coronary Artery Disease: Therapeutics and Drug Discovery

Miao Wang (Herausgeber)

Buch | Softcover
339 Seiten
2021 | 1st ed. 2020
Springer Verlag, Singapore
978-981-15-2519-3 (ISBN)
149,79 inkl. MwSt
This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease.

The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges.


The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued.


Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.

Dr. Miao Wang is a Professor and Head of the Laboratory of Vascular Biology and Pharmacology, State Key Laboratory of Cardiovascular Disease (SKLCD), National Center for Cardiovascular Disease, Peking Union Medical College & Chinese Academy of Medical Sciences. Before joining the SKLCD, Dr. Wang worked as the principal scientist at the Cardiovascular and Metabolic Disease Research Unit, Pfizer Inc. A lifetime member of the Sino-American Pharmaceutical Professionals Association, his research focuses on the mechanisms of coronary artery disease, particularly those related to inflammation and thrombosis, and on the translation of novel mechanistic insights into therapeutic innovations. He has published more than 30 research articles in the field’s leading journals.

Coronary Artery Disease: From Mechanism to Clinical Practice.- Evidence in guidelines for treatment of coronary artery disease.- Revascularization For Coronary Artery Disease: Principle And Challenges.- Antithrombotic drugs: pharmacology and perspectives.- Lipid modifying drugs: pharmacology and perspectives.- Anti-hypertensive drugs: pharmacology and perspectives.-  Pharmaceutical treatment for Heart failure.- Drug discovery for coronary artery disease

Erscheinungsdatum
Reihe/Serie Advances in Experimental Medicine and Biology ; 1177
Zusatzinfo 4 Illustrations, color; 3 Illustrations, black and white; IX, 339 p. 7 illus., 4 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizinische Fachgebiete Chirurgie Herz- / Thorax- / Gefäßchirurgie
Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
ISBN-10 981-15-2519-6 / 9811525196
ISBN-13 978-981-15-2519-3 / 9789811525193
Zustand Neuware
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