Sarcoidosis

Francesco Bonella is Associate Professor of Medicine and Head of the Division for Interstitial and Rare Lung Disease, Department of Pneumology, at the Ruhrlandklinik University Hospital (Essen, Germany). Daniel A. Culver is the Chair of the Department of Pulmonary Medicine in the Respiratory Institute at Cleveland Clinic (Cleveland, OH, USA) and the President of the World Association of Sarcoidosis and other Granulomatous Disorders. Dominique Israël-Biet is Professor Emeritus of pulmonary medicine of the Université de Paris (Paris, France).

Definition and history; Epidemiology: solving the jigsaw puzzle; Aetiopathogenesis, molecular determinants and immunological features; Unravelling the genetic basis of sarcoidosis; Principles of diagnosis; Conventional and nuclear imaging techniques; Pathological features and differential diagnosis; Serum and imaging biomarkers; Pulmonary sarcoidosis; Cardiac sarcoidosis; Granulomatous and nongranulomatous neurological sarcoidosis; Cutaneous sarcoidosis; The calcium–kidney–bone axis; Non-organ-specific manifestations; Hepatic and splenic involvement; Sarcoidosis-associated pulmonary hypertension; Rheumatological manifestations; Ocular sarcoidosis; Paediatric sarcoidosis; The manifestations of rare organ sarcoidosis; When to treat sarcoidosis; Treating sarcoidosis and potential new drugs; Quality-of-life assessment