Clinical Molecular Diagnostics

Editor Shiyang Pan, M.D, Ph.D., is a chief physician and the director of the Dept. of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Editor Jinhai Tang is a professor at The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Part 1 Principles of Clinical Molecular Diagnostics.- 1 Molecules of Diseases and Their Detection Methods.- 2 Assay Performance Evaluation.- 3 Establishment of Biological Reference Interval.- 4 Ethics: Informed Consent, Patient Privacy.- 5 Bioinformatics.- 6 Report and Consultation.- 7 Factors Associated with Variation.- 8 Quality Control and Quality Assurance.- 9 Precision Medicine.- Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ.- 10 Molecules in Body Systems.- 11 Molecules in Signal Pathways.- 12 Endocrine and Metabolism.- 13 Immune System.- 14 Lipoproteins.- 15 Transport and Carrier Proteins.- 16 Coagulation and Fibrinolysis.- 17 Cardiovascular System.- 18 Pregnancy.- 19 Urine.- 20 Bone.- 21 Cancer.- 22 Translation Research of Novel Biomarker.- Part 3 Advanced Molecular Diagnostic Techniques.- 23 Next-generation Sequencing (NGS).- 24 Digital PCR.- 25 Biosensor.- 26 Microfluidic Chip.- 27 Liquid Biopsy.- 28 Molecular Targeted Imaging.- 29 Fluorescence in Situ Hybridization.- 30 Circulating DNA Quantification.- 31 DNA Methylation Detection Techniques.- Part 4 Disease Presentation and Clinical Laboratory Procedures.- 32 Immunological Disorders.- 33 Liver Diseases.- 34 Pancreatic Diseases.- 35 Digestive Tract Disease.- 36 Kidney Diseases.- 37 Cardiovascular Disease.- 38 Lung Disease.- 39 Blood Disorders.- 40 Endocrine and Metabolic Diseases.- 41 Neurological Disease.- 42 Reproductive Organ Cancer.- 43 Reproductive Organ Cancer.- 44 Transplant Matching.- 45 Paternity Test.