Clinical Molecular Diagnostics -

Clinical Molecular Diagnostics

Shiyang Pan, Jinhai Tang (Herausgeber)

Buch | Hardcover
889 Seiten
2021 | 1st ed. 2021
Springer Verlag, Singapore
978-981-16-1036-3 (ISBN)
267,49 inkl. MwSt
This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs.
This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, especially from different diseased organs. It lets readers to understand and realize precision healthcare.

Editor Shiyang Pan, M.D, Ph.D., is a chief physician and the director of the Dept. of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Editor Jinhai Tang is a professor at The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Part I Principles of Clinical Molecular DiagnosticsChapter 1 Molecules of Diseases and Their Detection Methods



Chapter 2 Assay Performance Evaluation



Chapter 3 Establishment of Biological Reference Interval



Chapter 4 Ethics: Informed Consent, Patient Privacy



Chapter 5 Bioinformatics



Chapter 6 Report and Consultation



Chapter 7 Factors Associated with Variation



Chapter 8 Quality Control and Quality Assurance



Chapter 9 Precision Medicine



Part 2 Molecular Biomarkers and Signals from Diseased Functional Organ



Chapter 10 Molecules in Body Systems



Chapter 11 Molecules in Signal Pathways



Chapter 12 Endocrine and Metabolism



Chapter 13 Immune System



Chapter 14 Lipoproteins



Chapter 15 Transport and Carrier Proteins



Chapter 16 Coagulation and Fibrinolysis



Chapter 17 Cardiovascular System



Chapter 18 Pregnancy



Chapter 19 Urine



Chapter 20 Bone



Chapter 21 Cancer



Chapter 22 Translation Research of Novel Biomarker



Part 3 Advanced Molecular Diagnostic Techniques



Chapter 23 Next-generation Sequencing (NGS)



Chapter 24 Digital PCR



Chapter 25 Biosensor



Chapter 26 Microfluidic Chip



Chapter 27 Liquid Biopsy



Chapter 28 Molecular Targeted Imaging



Chapter 29 Fluorescence in Situ Hybridization



Chapter 30 Circulating DNA Quantification



Chapter 31 DNA Methylation Detection Techniques



Part 4 Disease Presentation and Clinical Laboratory Procedures



Chapter 32 Immunological Disorders



Chapter 33 Liver Diseases



Chapter 34 Pancreatic Diseases



Chapter 35 Digestive Tract Disease



Chapter 36 Kidney Diseases



Chapter 37 Cardiovascular Disease



Chapter 38 Lung Disease



Chapter 39 Blood Disorders



Chapter 40 Endocrine and Metabolic Diseases



Chapter 41 Neurological Disease



Chapter 42 Reproductive Organ Cancer



Chapter 43 Reproductive Organ Cancer



Chapter 44 Transplant Matching



Chapter 45 Paternity Test

Erscheinungsdatum
Zusatzinfo 250 Tables, color; 137 Illustrations, color; 7 Illustrations, black and white; XXVIII, 889 p. 144 illus., 137 illus. in color.
Verlagsort Singapore
Sprache englisch
Maße 210 x 279 mm
Gewicht 2914 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 2. Studienabschnitt (Klinik) Pathologie
Schlagworte clinical validation • diseased organs • evidence based laboratory medicine • Molecular biomarkers • Molecular Diagnostic Tests
ISBN-10 981-16-1036-3 / 9811610363
ISBN-13 978-981-16-1036-3 / 9789811610363
Zustand Neuware
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