Stereotactic and Functional Neurosurgery

Nader Pouratian, MD, PhD.  Professor and Vice Chair, Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Sameer A. Sheth, MD, PhDAssociate Professor, Vice-Chair of Clinical Research, McNair Scholar, Department of Neurosurgery, Baylor College of MedicineHouston, TX, USA

Part I: Achieving Stereotactic Precision.- Traditional and Mini-Frames.- Stereotactic Robots.- Intraoperative Magnetic Resonance Imaging and Computed Tomoraphy.- Frameless Image Guidance in Stereotactic Radiosurgery.- Part II: Defining Trajectories and Targets.- Principles of Safe Sterotactic Trajectories.- Structural Imaging and Target Visualization.- Network-Based Imaging and Connections.- Microelectrode Recording in Neurosurgical Patients.- Local Field Potentials and ECoG.- Awake Testing to Confirm Target Engagement.- Cloud-Based Stereotactic and Functional Neurosurgery and Registries.- Part III: The Biophysics of Stereotactic Therapy.- Responsive Neurostimulation.- Spinal Stimulation.- Peripheral Nerve Stimulation.- Non-Invasive Central Neuromodulation with Transcranial Magnetic Stimulation.- Ablation: Radiofrequency, Laser, and HIFU.- Radiosurgery.- Part IV: Diseases and Targets.- Parkinson's Disease: Deep Brain Stimulation.- Parkinson's Disease: Lesions.- Deep Brain Stimulation and Essential Tremor.- Essential Tremor: Lesions.- Dystonia.- Invasive Monitoring in Epilepsy Surgery.- Epilepsy: Mesial Temporal.- Neocortical Epilespy.- Stereotactic Neurosurgery for the Management and Treatment of Pediatric Epilepsy.- Epilepsy: Neuromodulation.- Deep Brain Stimulation for Treatment-Resistant Depression.- Deep Brain Stimulation for Obsessive Compulsive Disorder.- Stereotactic Lesion Procedures for Obsessive-Compulsive Disorder.- Deep Brain Stimulation for Gilles de la Tourette Syndrome.- Neuromodulation for Chronic Pain.- Chronic Pain: Lesion.- Deep Brain Stimulation for Cluster Headache.- Part V: The Future of Functional Neurosurgery.- Developing New Indications: Strategies and Hurdles to Discovery.- Imaging: Patient Selection, Targeting, and Outcome Biomarkers.- The Design of Clinical Studies for Neuromodulation.- Registries and Big Data.