Pseudogenes
Springer-Verlag New York Inc.
978-1-0716-1502-7 (ISBN)
Authoritative and cutting-edge, Pseudogenes: Functions and Protocols, Second Edition aims to be a practical guide to researches, useful to help further their study in this field.
Pseudogenes: Four Decades of Discovery.- Methods to Identify and Study the Evolution of Pseudogenes using a Phylogenetic Approach.- Computational Methods For Pseudogene Annotation Based on Sequence Homology.- A Methodology to Study pseudogenized lincRNAs.- GENCODE Pseudogenes.- Comprehensive Detection of Pseudogenes Transcribed by Readthrough.- Mathematical modeling of ceRNA-based interactions.- Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation.- Pseudogenes as Competitive Endogenous RNAs: Testing miRNA Dependency.- An Overview of the Computational Models Dealing with the Regulatory ceRNA Mechanism and ceRNA Deregulation in Cancer.- Studying the Oncosuppressive Functions of PTENP1 as a ceRNA.- Methods to Study Protein-Binding to Pseudogene Transcript.- Chromatin Regulation at Parental Gene Promoters by Pseudogene Sense lncRNAs.- Pseudogenes: A Novel Source of Trans Acting Antisense RNAs.- Methods to Study Translated Pseudogenes: Recombinant Expression and Complementation, Targeted Proteomics and RNA Profiling.- A Restriction Endonuclease-Based Assay to distinguish NANOGP8 Retrogene from Parental NANOG.- CRISPR/Cas Technologies Applied to Pseudogenes.- Strategies to Study the Functions of Pseudogenes in Mouse Models of Cancer.- Pseudogene Profiling For Cancer Subtype Classification.- Pseudogenes as Biomarkers and Therapeutic Targets in Human Cancers.- Methods for the Detection of Circulating Pseudogenes and their use as Cancer Biomarker.- Dealing with Pseudogenes in Molecular Diagnostics in the Next Generation Sequencing Era.
Erscheinungsdatum | 02.07.2021 |
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Reihe/Serie | Methods in Molecular Biology ; 2324 |
Zusatzinfo | 78 Illustrations, color; XIII, 384 p. 78 illus. in color. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
ISBN-10 | 1-0716-1502-5 / 1071615025 |
ISBN-13 | 978-1-0716-1502-7 / 9781071615027 |
Zustand | Neuware |
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