Inflammation and Epilepsy: New Vistas
Springer International Publishing (Verlag)
978-3-030-67402-1 (ISBN)
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
lt;p>Damir Janigro
Department of Physiology and Biophysics
Case Western Reserve UniversityCleveland
Ohio
USA
Astrid Nehlig
INSERM
Strasbourg
France
Nicola Marchi
Institut de Génomique Fonctionnelle
University of MontpellierMontpellier
FrancePro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium.- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders.- Glial Mechanisms of Inflammation during Seizures.- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy.- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions.- Autoantibodies, Encephalopathies and Epilepsy.- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline.- Ketogenic Diet, Inflammation and Epilepsy.- Role of Regulatory T cells in Epilepsy.- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy.
| Erscheinungsdatum | 20.05.2021 |
|---|---|
| Reihe/Serie | Progress in Inflammation Research |
| Zusatzinfo | VIII, 237 p. 1 illus. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 529 g |
| Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
| Schlagworte | Brain-body Axis • Cerebrovasculature • Epilepsy • Infectious Diseases • inflammatory mechanisms • Maternal and Perinatal Influences • microbiota • Neurological Diseases • therapeutic targets |
| ISBN-10 | 3-030-67402-9 / 3030674029 |
| ISBN-13 | 978-3-030-67402-1 / 9783030674021 |
| Zustand | Neuware |
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