Clinical Nephrotoxins -

Clinical Nephrotoxins

Renal Injury from Drugs and Chemicals
Buch | Hardcover
730 Seiten
2003 | 2nd Revised edition
Kluwer Academic Publishers (Verlag)
978-1-4020-1277-8 (ISBN)
319,93 inkl. MwSt
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A comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys, this second edition offers expanded information regarding the paediatric age group and provides up-to-date references.
This is a comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The book consists of a general part dealing with themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. The second part includes the specific drugs, for instance the anti-infectious agents, anti-inflammatory drugs, cardiovascular drugs, anti-cancer drugs and so forth. The last part deals with the prevention consisting of urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this second and completely revised edition, several new topics were added, information regarding the paediatric age group was expanded and up-to-date references provided, while remaining true to the concept of a multinational author book.

1. Clinical relevance. 2. Renal handling of drugs and xenobiotics. 3. Pharmacovigilance. 4. Immunologically-mediated toxin-induced renal disease. 5. Cellular mechanisms of nephrotoxicity. 6. Animal models for the assessment of acute renal dysfunction and injury. 7. Renal cell culture models. 8. Aminoglycosides and vancomycin. 9. Beta-lactam antibiotics. 10. Amphotericin B. 11. Sulfonamides, sulfadiazine, trimethoprim-sulfamethoxazole, pentamidine, pyrimethamine, dapsone, quinolones. 12. Antiviral agents. 13. Analgesics and 5-aminosalicylic acid. 14. Non-steroidal anti-inflammatory drugs. 15. Gold salts, D-penicillamine and allopurinol. 16. Angiotensin I converting enzyme inhibitors and angiotensin II receptor antagonists. 17. Diuretics. 18. Anticancer drugs. 19. Anesthetic agents. 20. Illicit drug abuse. 21. Cysclosporine, tacrolimus and sirolimus. 22. Immunomodulators: interleukins, interferons, and the OKT3 monoclonal antibody. 23. Radiocontrast agents. 24. Lead nephropathy. 25. Cadmium nephropathy. 26. Mercury nephropathy. 27. Exposure to hydrocarbons, silicon-containing compounds and pesticides. 28. Lithium nephropathy. 29. Aristolochic acid nephropathy after Chinese herb remedies. 30. Balkan endemic nephropathy. 31. Nephrotoxins in Africa. 32. Paraphenylene diamine hair dye poisoning. 33. Urinary biomarkers and nephrotoxicity. 34. Pharmacological aspects of nephrotoxicity. 35. Principles of drug usage in dialysis patients.

Sprache englisch
Einbandart gebunden
Themenwelt Medizinische Fachgebiete Innere Medizin Nephrologie
ISBN-10 1-4020-1277-2 / 1402012772
ISBN-13 978-1-4020-1277-8 / 9781402012778
Zustand Neuware
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