Phosphoinositides in Subcellular Targeting and Enzyme Activation
Springer Berlin (Verlag)
978-3-540-00950-4 (ISBN)
Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.
List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.
From the reviews:
"The book consists of seven chapters that focus on the various functions of PtdIns. ... summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)
| Erscheint lt. Verlag | 15.9.2003 |
|---|---|
| Reihe/Serie | Current Topics in Microbiology and Immunology |
| Zusatzinfo | IX, 209 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 450 g |
| Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
| Schlagworte | Chemotaxis • endocytosis • Enzym • Immunologie • Microorganism • Mikrobiologie • phagocytosis • phosphoinositide • Protein • proteins • signal transduction |
| ISBN-10 | 3-540-00950-7 / 3540009507 |
| ISBN-13 | 978-3-540-00950-4 / 9783540009504 |
| Zustand | Neuware |
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