Management of Bone Disease and Kidney Failure in Multiple Myeloma

Elena Zamagni, MD, PhDUniversity of BolognaDepartment of Experimental, Diagnostic and Specialty MedicineBologna, Emilia-RomagnaItaly
Elena Zamagni is Assistant Professor of Hematology at the University of Bologna, Italy. She received her medical degree from the University of Bologna, where she also served her residency in hematology. She obtained her PhD in Clinical Hematology at the University of Bologna in May 2005.
Her research interests include areas related to multiple myeloma, in particular the role of high dose therapy with stem cell support, prognostic factors, and imaging techniques.
She has published over 90 papers in peer-reviewed journals, mainly in the field of plasma cell dyscrasia. She has contributed to the educational session of the Italian Society of Haematology. She is an active member of the board of the GIMEMA myeloma working party and she has served as the scientific secretary and as the principal investigator in several national randomized trials in multiple myeloma. She is also a member of the Italian Society of Haematology and of the International Myeloma Working Group. She has served on the EHA's Scientific Program Committee since 2017. 

1. Introduction: Management of Bone Disease and Kidney Failure in Multiple Myeloma.- 2. The Pathophysiology of Myeloma Bone Disease: Bone Remodelling and the Role of Osteoclasts.-  3. The Pathophysiology of Myeloma Bone Disease: Role of Osteoblasts and Osteocytes.- 4. Imaging Techniques in Staging and Early Phases.- 5. Imaging Techniques for Response Assessment and Follow-up.- 6. New Perspectives in Imaging Techniques.- 7. Therapy of Myeloma Bone Disease.- 8. Orthopedic Management in Multiple Myeloma: What is the Role and When? .- 9. The Pathophysiology of Kidney Involvement in Multiple Myeloma and Monoclonal Related Disorders.- 10. Treatment of Multiple Myeloma with Kidney Involvement.