Gestational Diabetes

From Diagnosis to Treatment

Buch | Hardcover

570 Seiten

2020
Nova Science Publishers Inc (Verlag)
978-1-5361-8335-1 (ISBN)

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Gestational diabetes, because of its not only high prevalence but also resulting complications in both mother and fetus makes it one of the most important problem of a pregnant woman. The exact cause of gestational diabetes is unknown. Obviously, there is no one reason for the development of the disease. Placental hormones likely play a role. Insulin resistance is in the center and some factors like adipokines, lipids, inflammation, oxidative stress, heavy metals, gut microbiota, autoimmunity, metabolomics, genetic factors and vitamin D are the determinants for the development of insulin resistance and disease itself. Worldwide distribution of the disease changes according to geography. Ethnic factors also play role. Although some well-known risk factors have role in the development of the disease, 1 in 20 women without any risk factors also develop GDM. There is no universal screening and diagnostic methods. Some countries use universal screening some others prefer selective screening of women with risk factors. In addition, some suggest use of one-step diagnosis, while others two-step. The most challenging issue is use of some biomarkers in early (first trimester) diagnosis of pregnancy to prevent development of GDM. Many modalities are used in treatment. Medical nutrition therapy is still the basis of management. Exercise has some roles, too. Besides pharmacotherapies like insulin and oral antidiabetics, some modern modalities like insulin pump therapy together with continuous glucose monitoring, telemedicine, dietary supplements like myoinositols are also covered in this book. Monitorization is important in diabetes and role of nurses in follow-up is incontrovertible. If not treated well, both fetus and mother are open to complications. From congenital malformations to macrosomia, if inevitable, proper management of these problems has to be considered. Some comorbidities like hypertension, thyroid problems and psychosocial stress complicate the problem further. Fetal monitorization, time and type of delivery and management of glycaemia during peripartum period are the issues to be considered towards to end of pregnancy. The problem does not finish with the birth of baby. Both mother and newborn has to be followed for the development of future problems like postpartum diabetes and obesity. Nutrition and benefits of breastfeeding are important points for the health of the baby. In addition, every efforts has to be spent to prevent recurrence of the disease in subsequent pregnancies. The most important instrument against fighting a disease is information i.e. how much we know about it. Understanding the problem thoroughly strengthens our hands to cope and overcome it more easily. The main target of this book is to handle every aspect of the disease from diagnosis to treatment as evident from the title. It is a candidate for a reference guide in this subject. It includes most recent and update data on gestational diabetes.

Preface; Maternal Metabolism and Nutrient Delivery to Fetus; The Impairments of Glucose Metabolism ın Pathophysıology of Ges-tatıonal Dıabetes Mellıtus; The Role of the Human Placenta in Pathophysiology of Gestational Diabetes Mellitus; The Fetal Metabo-lism and the Pathophysiological Mechanisms of Fetal Complications; Insulin Resistance in Pregnancy and Etıopathogenesıs of Gesta-tional Diabetes Mellitus; The Effect of Obesity on the Development of Gestational Diabetes Mellitus; Adipokines: Role in Etiopatho-genesis of Gestational Diabetes Mellitus; Lipid Metabolism in Pathophysiology of Gestational Diabetes Mellitus; Gestational Diabetes Mellitus and Inflammation; The Roles of Oxidative Stress and Heavy Metal Toxicity in the Pathogenesis of Gestational Diabetes Mellitus; Gut Mıcrobıota and Etıopathogenesıs of Gestatıonal Dıabetes Mellıtus; Autoimmunity: Role in Etiopathogenesis of Gesta-tional Diabetes Mellitus; Environmental and Dietary Factors: Role ın Etıopathogenesıs of Gestatıonal Dıabetes Mellıtus; Metabolom-ics: Role ın Etıopathogenesis of Gestatıonal Dıabetes Mellıtus; Genetic and Epigenetic Factors: Role ın Etıopathogenesis of Gestatıonal Dıabetes Mellıtus; Vitamin D and Gestational Diabetes Mellitus; Epidemiology and Prevalence of Gestational Diabetes Mellitus; Epi-demiology and Approach to Gestational Diabetes Mellitus in India; Geographic and Ethnic Variations in the Incidence of Gestational Diabetes Mellitus; Risk Factors for Gestational Diabetes Mellitus; Risk Scores for Selective Screening for Gestational Diabetes in Sub Saharan Africa; Definition, History, Diagnosis and General Features of Gestational Diabetes Mellitus; Diagnosis and Screening Meth-ods in Gestational Diabetes Mellitus; Comparison of Screening Methods in Gestational Diabetes Mellitus; Hyperglycemia in Pregnan-cy among South Asian Women: Experience from Universal Screening and Multi-Disciplinary Management; Biomarkers in the Early Diagnosis of Gestational Diabetes Mellitus; Glycemic Targets ın Gestatıonal Diabetes Mellitus; Which Is More Important in Gesta-tional Diabetes Mellitus: Fasting or Postprandial Blood Glucose?; Glucose Monitoring in Management of Gestational Diabetes Melli-tus; Medical Nutrition Therapy ın Gestatıonal Dıabetes Mellıtus; Physical Activity and Exercise in Gestational Diabetes Mellitus; In-sulın Therapy in Gestational Diabetes Mellitus; Insulin Pump Therapy and Continuous Glucose Monitoring Systems in Pregnancy with Pregestational and Gestational Diabetes; Oral Antihyperglycemic Agents in the Treatment of Gestational Diabetes Mellitus; Role of Myoinositols in Gestational Diabetes Mellitus; Management of Obesity in Pregnancies with Gestational Diabetes Mellitus; The Effect of Treatment on Outcomes in Gestational Diabetes Mellitus; Role of Diabetes Nurse in the Management of Gestational Diabetes Mellitus; Health 4.0 to Facilitate Effective Self-Care for Patients with Gestational Diabetes Mellitus; Integrating Gestational Diabetes Mellitus Management in Primary Health Care; Maternal Complications of Gestatıonal Dıabetes Mellıtus; Fetal and Neonatal Complica-tions of Gestational Diabetes Mellitus; Congenital Malformations in Gestational Diabetes Mellitus; Maternal Hypoglycemia; Manage-ment of Macrosomic Baby; Hypertension in Gestational Diabetes Mellitus: Diagnosis and Treatment; Thyroid Dysfunction in Women with Gestational Diabetes Mellitus; The Cardiovascular Disease as a Complication of Gestational Diabetes Mellitus; Psychosocial Stress in Gestational Diabetes Mellitus and Its Management; Fetal Monitorization ın Gestatıonal Dıabetes Mellıtus; Optımal Tıme and Mode of Delıvery in Gestational Diabetes Mellitus; Management of Glycemia during and after Labor; Postpartum Management of Mother and Infant in Gestational Diabetes Mellitus; The Protective Effect of Breastfeeding and Postpartum Weight Loss against the Development of Diabetes in Japanese Women with a History of Gestational Diabetes; Nutritional Problems in Children of Mothers with Gestational Diabetes Mellitus; Increasing Cumulative Incidence of Diabetes after Gestational Diabetes: A Double Cohort, Long-Term Follow-Up in a Danish Population; Predictors of Postpartum Diabetes Mellitus; Determinants of Recurrence in Gestational Dia-betes Mellitus; Index.

Erscheinungsdatum	02.11.2020
Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	1423 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie
ISBN-10	1-5361-8335-0 / 1536183350
ISBN-13	978-1-5361-8335-1 / 9781536183351
Zustand	Neuware