The American Psychiatric Publishing Textbook of Psychopharmacology

Part I: Principles of Psychopharmacology. Neurotransmitters, receptors, signal transduction, and second messengers in psychiatric disorders. Basic principles of molecular biology and genomics. Chemical neuroanatomy of the primate brain. Electrophysiology. Animal models. Psychoneuroendocrinology. Principles of pharmacokinetics and pharmacodynamics. Brain-immune system interactions: relevance to the pathophysiology and treatment of neuropsychiatric disorders. Brain imaging in psychopharmacology. Statistics and clinical trial design in psychopharmacology. Pharmacoeconomics. Part II: Classes of Psychiatric Treatments: animal and human pharmacology. Antidepressants and Anxiolytics. Tricyclic and tetracyclic drugs. Fluoxetine. Sertraline. Paroxetine. Fluvoxamine. Citalopram and s-citalopram. Monoamine oxidase inhibitors. Trazodone and nefazodone. Bupropion. Mirtazapine. Venlafaxine. Duloxetine and milnacipran. Benzodiazepines. Buspirone and gepirone. Investigational treatments for mood and anxiety disorders: CRH receptor antagonists, NK-1 receptor antagonists, and glucocorticoid receptor antagonists. Antipsychotics. Classic antipsychotic medications. Clozapine. Olanzapine. Quetiapine. Aripiprazole. Risperidone. Ziprasidone. Drugs to treat extrapyramidal side effects. Drugs for Treatment of Bipolar Disorder. Lithium. Valproate. Carbamazepine and oxcarbazepine. Gabapentin. Lamotrigine. Topiramate. Other Agents. Cognitive enhancers. Sedative-hypnotics. Psychostimulants in psychiatry: amphetamine, methylphenidate, and modafinil. Electroconvulsive therapy. Part III: Clinical Psychobiology and Psychiatric Syndromes. Biology of mood disorders. Neurobiology of schizophrenia. Neurobiology of anxiety disorders. Biology of Alzheimer's disease. Neurobiology of substance abuse disorders. Biology of eating disorders. Biology of personality disorders. Part IV: Psychopharmacological Treatment. Treatment of depression. Treatment of bipolar disorder. Treatment of schizophrenia. Treatment of anxiety disorders. Management of noncognitive symptoms of dementia: behavioral and psychological symptoms of dementia. Treatment of childhood and adolescent disorders. Treatment of substance-related disorders. Treatment of eating disorders. Treatment of agitation and aggression in the elderly. Treatment of personality disorders. Psychiatric emergencies. Treatment during late life. Psychopharmacology during pregnancy and lactation. Treatment of insomnia. Index.