Leukemia: Advances in Research and Treatment

1. All trans retinoic acid as a targeting drug for differentiation therapy in acute promyelocytic leukemia.- 2. Hairy cell leukemia: New understanding of biology and treatment.- 3. Uses of polymerase chain reaction in leukemia: Detection of minimal residual disease and identification of novel genetic mutations.- 4. The cell surface receptor encoded by the proto-oncogene KIT and its ligand.- 5. Human T-cell lymphoma/leukemia retroviruses and malignancy.- 6. Fludarabine phosphate in the treatment of chronic lymphocytic leukemia: Biology, clinical impact, and future directions.- 7. The role of immunotherapy in the treatment of acute myeloblastic leukemia: From allogeneic bone marrow transplantation to the application of interleukin 2.- 8. Detection of minimal residual disease in ALL.- 9. Cytokines and myeloid-specific genes: Patterns of expression and possible role in proliferation and differentiation of acute myelogenous leukemia cells.- 10. The immunological treatment of human marrow in vitro in transplant biology.- 11. Monoclonal antibodies in the treatment of myelogenous leukemias.- 12. Prognosis and therapy of myelodysplastic syndromes.- 13. Multidrug resistance in leukemia.- 14. The molecular pathogenesis of the Philadelphia-positive leukemias: Implications for diagnosis and therapy.