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The Large Intestine

Physiology, Pathophysiology, and Disease
Buch | Hardcover
928 Seiten
1991
Lippincott Williams and Wilkins (Verlag)
978-0-88167-777-5 (ISBN)
209,95 inkl. MwSt
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A review of the epidemiology, anatomy, physiology, pathophysiology and clinical features of colorectal diseases. It examines normal physiology and anatomy as well as structural and functional abnormalities of the large intestine, and it also asseses approaches to diagnosis and treatment.
This work brings together more than 50 leading figures in the basic and clinical enteric sciences to conduct a review of the epidemiology, anatomy, physiology, pathophysiology, and clinical features of colorectal diseases. The editors and contributors balance coverage of the expanding base of enteric science, the pathophysiologic mechanisms underlying colonic disease, and specific colorectal diseases. By integrating key scientific principles with clinical observations, these specialists establish a rational basis for the differential diagnosis and treatment of infectious, inflammatory, neoplastic, and functional diseases and disorders of the large intestine. The first part of the book examines the normal anatomy and physiology and structural and functional abnormalities of the large intestine. The second part assesses the clinical utility of all available diagnostic studies and addresses epidemiologic and etiologic issues such as screening guidelines for colorectal disease and the role of diet and fibre. The third part critically evaluates current approaches to the diagnosis and medical and surgical treatment of all major diseases seen in practice.

Part 1 Structure and function of the large intestine: embryology and developmental abnormalities of the large intestine, R.A. Cobb and R.C.N. Williamson; gross and microscopic anatomy of the large intestine, J. Christensen; structure-function relationships - lessons from other species, Michael I. McBurney and Peter J. Van Soest; the colonic flora, fermentation, and large bowel digestive function, G.T. McFarlane and J.H. Cummings; motor functions of the colon, Jan D. Huizinga and Edwin E. Daniel; functions of the anorectum - defecation and continence, Ghislain Devroede; colonic fluid and electrolyte transport in health and disease, Henry J. Binder, et al; regulation of colonic transport by the autonomic nervous system, Helen J. Cooke; response of the colon to injury - inflammation, immunity, and mucus, Steven R. Martin and W. Allan Walker. Part 2 General clinical features of colo-rectal disease: limitations of epidemiologic methods in the study of colonic disorders, Albert I. Mendeloff; diet, fibre and colorectal disease - critical appraisal, Martin Eastwood; radiology of the large intestine, Claire E. Bender; endoscopy of the colon, Jonathan E. Clain; clinical application of diagnostic tests in selected colonic disorders, J.B. Kirsner and M.O. Blackstone; value of colorectal biopsies - a critical appraisal, Teri A. Longacre and Cecilia M. Fenoglio-Preiser; screening for colorectal disease; Douglas B. McGill and David A. Ahlquist. Part 3 Specific diseases of the large intestine: novel aspects of the pathophysiology of parasitic infections of the colon, Stephen M. Collins; parasitic infections of the large intestine, Henry Zaiman and Roy G. Shorter; bacterial infections - pathophysiology, clinical features and treatment, Mitchell B. Cohen, et al; infections of the large intestine in the immunocompromised host, Phillip D. Smith, et al; etiology of chronic ulcerative colitis and Crohn's Disease, V.S. Chadwick; challenges in inflammatory bowel diseases, Gary Gitnick; critical evaluation of the medical therapy of inflammatory bowel disease, Henry D. Janowitz and Jeffrey J. Bilotta; etiology of large bowel cancer, Dennis J. Ahnen; neoplasia of the colorectum - natural history and prognosis of colorectal cancer, Richard E. Wilson and John H. Donohue; diverticular disease of the colon, Adam N. Smith; megacolon, Sidney F. Phillips; irritable bowel syndrome, W. Grant Thompson; bleeding from the colon, Paul C. Shellito and Leslie W. Ottinger. (Part contents).

Erscheint lt. Verlag 1.9.1991
Zusatzinfo 113 tables, 249 line drawings, 136 half-tones, 27 colour figures
Verlagsort Philadelphia
Sprache englisch
Maße 216 x 279 mm
Gewicht 3310 g
Themenwelt Medizinische Fachgebiete Innere Medizin Gastroenterologie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 0-88167-777-9 / 0881677779
ISBN-13 978-0-88167-777-5 / 9780881677775
Zustand Neuware
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