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Laminins

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Buch | Hardcover
321 Seiten
1996
Taylor and Francis (Verlag)
978-3-7186-5807-7 (ISBN)
219,95 inkl. MwSt
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This work provides detailed knowledge about the molecular features of the laminins and describes the structure-function relationships and interactions that define their biologically active domains. Gene coding for laminins and genetic diseases affecting laminins are covered.
This work provides detailed knowledge about the molecular features of the laminins and describes the structure-function relationships and interactions that define their biologically active domains. Many of the discoveries concerning the tissue-specific laminins and the role of different laminins are addressed. By covering topics such as gene coding for laminins, genetic diseases affecting laminins, evolutionary aspects, embryonic development, apoptosis, neurite outgrowth and cancer, this study provides a basis for understanding the role of laminins in development and disease.

Biosynthesis, tissue distribution and isolation of laminins; structure of laminins and their chain assembly; laminin genes - structure, regulation and mutations in disease; laminins of epidermal structures; binding of laminins to extracellular structures; binding of laminins to extracellular matrix components; integrin-mediated cellular interactions with laminins; non-integrin laminin receptors; laminin isoferms in development; basement membrane as a differentiation and survival factor; drosophila laminin; laminins during neurite growth and nerve regeneration; interaction of tumor cells with basement membranes and laminin-1; dystroglycan - a novel laminin receptor and its involvement in the pathogenesis of muscular dystrophies.

Zusatzinfo Farb., s/w. Abb.
Verlagsort Chur
Sprache englisch
Gewicht 888 g
Themenwelt Medizinische Fachgebiete Chirurgie Unfallchirurgie / Orthopädie
Studium 2. Studienabschnitt (Klinik) Humangenetik
Naturwissenschaften Biologie Zellbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 3-7186-5807-0 / 3718658070
ISBN-13 978-3-7186-5807-7 / 9783718658077
Zustand Neuware
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