Essentials of the Adult Neurogenic Bladder

Jacques Corcos MSC, MD, FRCS Urologist Montreal, Canada Editor of 9 books including the 3 initial edition of the Textbook of the neurogenic bladder. Former General secretary of the International Continence Society. Member of several scientific societies. More than 200 peer reviewed published articles David Ginsberg MD, FAAS Urologist Los Angeles, USA Editor of the previous edition of the textbook of the neurogenic bladder, author of multiple book chapters and of 75 peer reviewed articles. Very active member of SUFU and AUA. Thomas Kessler MD Urologist Zurich, Swiss President of the International Neuro urology association, Director of Neurourology Unit at Balgrist medical Center, Zurich. Author of more than 150 peer reviewed articles and book chapters. Gilles Karsenty MD Urologist Marseille, France Editor of the previous edition of the textbook, Director of the functional urology unit at Marseille University. Author of more than 100 peer reviewed articles.

Foreword. Contributors. Introduction. PART I. EPIDEMIOLOGY AND PATHOPHYSIOLOGY OF NEUROGENIC BLADDERS. Epidemiology of Neurogenic Bladder. Pathophysiology of Detrusor Overactivity. Pathophysiology of Detrusor Underactivity/ Acontractile Detrusor. Pathophysiology of the Low Compliant Bladder. Pathophysiology and Prevalence of Detrusor-Sphincter Dyssynergia. Pathophysiology of Autonomic Dysreflexia. Pathophysiology of Spinal Shock. PART II. NEUROLOGIC PATHOLOGIES RESPONSIBLE FOR THE DEVELOPMENT OF THE NEUROGENIC BLADDER. SECTION A: PERIPHERAL NEUROPATHIES. Systemic Illnesses (Diabetes Mellitus, Sarcoidosis, Alcoholism, and Porphyrias). Peripheral Neuropathies of the Lower Urinary Tract Following Pelvic Surgery and Radiation Therapy. SECTION B: HEREDITARY AND DEGENERATIVE DISEASES. Dementia and Lower Urinary Tract Dysfunction. Pathologies of the Basal Ganglia, Such as Parkinson’s and Huntington’s Diseases. SECTION C: DEMYELINATING NEUROPATHIES. Multiple Sclerosis, Transverse Myelitis, Tropical Spastic Paraparesis, Progressive Multifocal Leukoencephalopathy, Lyme Disease. SECTION D: VASCULAR PATHOLOGIES AND TUMORS OF THE BRAIN PRESENTS. Cerebrovascular Accidents, Intracranial Tumors, and Voiding Dysfunction. SECTION E: DISK PROLAPSE AND TUMORS OF THE SPINAL CORD. Tumors of the Spine, Intervertebral Disk Prolapse, the Cauda Equina Syndrome. Tethered Cord Syndrome. SECTION F: TRAUMATIC INJURIES OF THE CENTRAL NERVOUS SYSTEM. Spinal Cord Injury and Cerebral Trauma. SECTION G: OTHER NEUROLOGIC PATHOLOGIES RESPONSIBLE FOR NEUROGENIC BLADDER DYSFUNCTION. Cerebral Palsy, Cerebellar Ataxia, Aids, Phacomatosis, Neuromuscular Disorders, and Epilepsy. Syringomyelia and Lower Urinary Tract Dysfunction. PART III. EVALUATION OF NEUROGENIC BLADDER DYSFUNCTION. Considerations for the Focused Neuro-Urologic History and Physical Exam. Patient-Reported Outcome Measures in Neurogenic Bladder. Endoscopic Evaluation of Neurogenic Bladder. Evaluation of Neurogenic Lower Urinary Tract Dysfunction: Urodynamics. Electrophysiologic Evaluation: Basic Principles and Clinical Applications. Neuroimaging in the Evaluation of Neurogenic Bladder Dysfunction. Practical Guide to Diagnosis and Follow-Up of Patients with Neurogenic Bladder Dysfunction. PART IV. CLASSIFICATION. Classification of Lower Urinary Tract Dysfunction. PART V. TREATMENT. Conservative Treatment. Systemic, Intrathecal, and Intravesical Pharmacologic Treatment of Neurogenic Lower Urinary Tract Dysfunction. Management of Autonomic Dysreflexia. Peripheral and Intravesical Electrical Stimulation of the Bladder to Restore Bladder Function. Surgery to Improve Reservoir Function. Surgery to Improve Bladder Outlet Function. Urinary Diversion. Transappendicular Continent Cystostomy Technique (Mitrofanoff Principle). Tissue Engineering and Cell Therapies for Neurogenic Bladder Augmentation and Urinary Continence Restoration. Neuroprotection and Repair After Spinal Cord Injury. Neural Rerouting in Patients with Spinal Cord Injury. PART VI. SYNTHESIS OF TREATMENT. An Overview of Treatment Alternatives for Different Types of Neurogenic Bladder Dysfunction in Adults. PART VII. COMPLICATIONS. Complications Related to Neurogenic Bladder Dysfunction I: Infection, Lithiasis, and Neoplasia. Complications Related to Neurogenic Bladder Dysfunction II: Upper Urinary Tract. Benign Prostatic Hyperplasia and Lower Urinary Tract Symptoms in Men with Neurogenic Bladder. PART VIII. SEXUAL DYSFUNCTION AND REPRODUCTION IN NEUROLOGIC DISORDERS. Pathophysiology of Male Sexual Dysfunction after Spinal Cord Injury. Treatment Modalities for Erectile Dysfunction in Neurologic Patients. Fertility Issues in Men with Spinal Cord Injury. Pregnancy in Spinal Cord Injury. PART IX. PROGNOSIS AND FOLLOW-UP. Prognosis of Neurogenic Bladders. PART X. NEUROGENIC BLADDERS IN DEVELOPING COUNTRIES. Challenges of Management of Neurogenic Bladder in the Developing World. PART XI. REFERENCES FOR REPORTS AND GUIDELINES. Reports and Guidelines in Relation to Neurogenic Bladder Dysfunction: A Selection. Index.