Adult Craniopharyngiomas

Professor Emmanuel Jouanneau is a Neurosurgeon at Lyon University Hospital' and Professor of Neurosurgery at Lyon 1 University, France. After studying medicine at the same university, he completed his fellowship in Neurosurgery, focusing on adult brains tumors, skull base and pituitary surgery. He was a visiting fellow under Professor E. Laws for pituitary surgery and under Professor P. Cappabianca for pituitary and endoscopic surgery. He obtained his PhD after a year spent in the Immunologic laboratory at the Cedars Sinai Medical Center in Los Angeles. He now chairs the Skull Base and Pituitary Department at the Neurological Hospital of Lyon, the second- largest such center in France. He is the co-head of the Pituitary Center of Lyon with G Raverot. Professor Gerald Raverot is an endocrinologist at Lyon University Hospital and Professor of Endocrinology at Lyon1 University, France. He received his medical degree from The University of Medicine of Lyon, France and completed an endocrinology fellowship with a focus in pituitary disorders in France. He was then a visiting fellow in Larry Jameson's laboratory at Northwestern University (Chicago, USA), where he completed his PhD. He is joint head (with Pr Emmanuel Jouanneau, neurosurgeon) of the Pituitary Center, Lyon, France. He leads a research team dedicated to "Pathophysiology of pituitary tumor" at the INSERM Research Center U1052. His major research interests are pituitary tumor pathogenesis and identification of markers of aggressiveness allowing the identification of potential new therapies. He was the chair of the Special Interest Group on aggressive pituitary tumors, and he co-ordinated the European Society of Endocrinology guidelines on aggressive pituitary tumors and carcinoma.

Foreword.- Preface.- Acknowledgement.- 1. Histopathology and molecular pathology of craniopharyngioma in adults.- 2. Mouse models of craniopharyngioma.- 3. Epidemiology, clinical presentation and prognosis of adult-onset craniopharyngioma.- 4. Craniopharyngioma Diagnosis: A rationale for accurate MRI assessment of tumor topography and adhesion to the Hypothalamus.- 5. How far with surgery in the modern era of endoscopy: Nasal Route.- 6. Cranial Surgery for Adult Craniopharyngiomas: Techniques and indications.- 7. Definitive radiotherapy in adult population craniopharyngiomas.- 8. How to manager recurrent Craniopharymgiomas.- 9. Craniopharyngioma: Endocrinological aspects after surgery.- 10. Hypothalamic issue, QOL, Obesity management.- 11. Adult versus paediatric craniopharyngiomas: which differences?.- 12. Molecular Targets in Craniopharyngioma.- 13. Conclusions.