Macrophages & Cancer

Gloria H. Heppner, Amy M. Fulton

1. Macrophage Heterogeneity. 2. Activation of Macrophages for Tumor Cell Kill: Effector Mechanisms and Regulation. 3. Effector Mechanisms for Macrophage-Induced Cytostasis and Cytolysis of Tumor Cells. 4. Prostaglandin Regulation of Macrophage Function. 5. Genetic Control of Macrophage Antitumor Responses. 6. Tumor Associated Macrophages. 7. Macrophage-Lymphocyte Interactions in Tumor Recognition and Response. 8. Heterogeneity in Tumor and Macrophage Populations in the Recognition, Cytostasis and Cytolosis if Neoplastic Cells. 9. Therapeutic Circumvention of the Biologic Heterogeneity in Malignant Neoplasms by Tumoricidal Macrophages. 10. Strategies for Activation of Macrophages in Vivo for the Therapy if Metastatic Disease. 11. Macrophages and Development of Cancer. Index