Chimerism

A Clinical Guide

Buch | Softcover

XI, 200 Seiten

2018 | 1. Softcover reprint of the original 1st ed. 2018
Springer International Publishing (Verlag)
978-3-030-07881-2 (ISBN)

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This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented.
Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for cliniciansand researchers that will help guide patient management and stimulate investigative efforts.

Nicole L. Draper, MDUniversity of Colorado School of MedicineDepartment of PathologyAurora, CO USA

Fertilization and Early Embryonic Errors.- Pregnancy and Multiple Gestations.- Transplantation and Transfusion.- Relationship Testing and Forensics.- Prenatal Genetic Testing and Screening.- Blood Typing Discrepancies.- Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease.- Passenger Lymphocyte Syndrome.- Chimerism: A Clinical Guide to Tolerance Induction.- Autoimmune Disease.- Cancer.

"The purpose is to provide a single source of the 'current understanding of chimerism.' This worthy objective is well met by this book. ... This book would be of interest to anyone working in blood bank/transfusion services or molecular genetic testing, general anatomical pathologists and specialists in forensics, autoimmune and/or obstetrical pathology. ... This is a fantastic book and a fascinating read. You will quickly get up to speed in an esoteric area which surprisingly impacts many aspects of medicine." (Valerie L. Ng, Doody's Book Reviews, November, 2018)

“The purpose is to provide a single source of the ‘current understanding of chimerism.’ This worthy objective is well met by this book. … This book would be of interest to anyone working in blood bank/transfusion services or molecular genetic testing, general anatomical pathologists and specialists in forensics, autoimmune and/or obstetrical pathology. … This is a fantastic book and a fascinating read. You will quickly get up to speed in an esoteric area which surprisingly impacts many aspects of medicine.” (Valerie L. Ng, Doody's Book Reviews, November, 2018)

Erscheint lt. Verlag	14.12.2018
Zusatzinfo	XI, 200 p. 20 illus., 15 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	448 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hämatologie
Schlagworte	dispermic chimerism • fetomaternal microchimerism • hematopoietic stem cell transplant • Solid Organ Transplant • tetragametic chimerism • transfusion microchimerism
ISBN-10	3-030-07881-7 / 3030078817
ISBN-13	978-3-030-07881-2 / 9783030078812
Zustand	Neuware