Cellular and Molecular Immunology

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

I. Introduction to Immunology. General Properties of Immune Responses. Cells and Tissues of the Immune System. II. Recognition of Antigens. Antibodies and Antigens. The Major Histocompatibility Complex. Antigen Processing and Presentation to Lymphocytes. Antigen Receptors and Accessory Molecules of T Lymphocytes. III. Maturation, Activation, and Regulation of Lymphocytes. Lymphocyte Maturation and Expression of Antigen Receptor Genes. Activation of T Lymphocytes. Activation of B Lymphocytes and Antibody Production. Immunological Tolerance. IV. Effector Mechanisms of Immune Responses. Cytokines. Innate Immunity. Cell-Mediated Immunity. Humoral Immunity. V. Immunity in Defence and Disease. Immunity to Microbes. Transplantation. Immunity to Tumors. Hypersensitivity Diseases and Autoimmunity. Immediate Hypersensitivity. Congenital and Acquired Immunodeficiencies.