AIDS Therapy

Raphael Dolin, MD, Maxwell Finland Professor of Medicine (Microbiology & Molecular Genetics), Harvard Medical School; Attending Physician, Beth Israel Deaconess Medical Center Brigham and Women's Hospital, Boston, Massachusetts

SECTION I: DIAGNOSIS OF HIV INFECTION 1Establishing the Diagnosis of HIV Infection SECTION II: ANTIRETROVIRAL THERAPY 2Zidovudine 3Didanosine 4Zalcitabine 5Stavudine 6Lamivudine 7Emtricitabine 8Abacavir 9Delavirdine 10Nevirapine 11Efavirenz 12Saquinavir 13Ritonavir 14Indinavir 15Nelfinavir 16Amprenavir 17Lopinavir (ABT 378) 18Tenofovir Disoproxil Fumarate 19Inhibitors of HIV Attachment and Fusion 20New Drugs in Development SECTION III: IMMUNE-BASED THERAPIES 21General Immune-Based Therapies in the Management of HIV-Infected Patients 22HIV Antigen-Specific Stimulation and Therapy Interruption SECTION IV: OTHER THERAPIES, INCLUDING ALTERNATIVE THERAPIES 23Alternative Therapies SECTION V: STRATEGIES FOR MANAGING ANTIRETROVIRAL THERAPIES 24Early Intervention: Acute HIV Infection Syndrome 25Postexposure Management 26Resistance Testing 27Management of Antiretroviral Therapy Failure 28Managing Pregnant Patients SECTION VI: DIAGNOSIS, THERAPY, AND PREVENTION OF OPPORTUNISTIC PROCESSES 29Pneumocystosis 30Toxoplasmosis 31Cryptosporidium, Isospora, and Cyclospora Infections 32Microsporidiosis 33Mycobacterium tuberculosis 34Mycobacterium avium Complex and other Atypical Mycobacterial Infections 35Bartonellosis 36Cryptococcosis 37Histoplasmosis 38Coccidioidomycosis 39Candidiasis 40Mycoses Caused by Moulds 41Herpes Simplex Virus Infections 42VZV Infections 43Cytomegalovirus Disease 44Human Herpesvirus-6 and -7 Infections 45EBV HHV8 46Viral Hepatitis 47Sexually Transmitted Human Papillomavirus Infection 48JC Virus Neurologic Infection 49Sexually Transmitted Diseases 50Kaposi Sarcoma 51Non-Hodgkin Lymphoma 52Primary Care: Daily Management SECTION VII: APPROACH TO SPECIFIC SYNDROMES 53Wasting Syndrome 54Neurologic Disease 55Dermatologic Disease 56Oropharyngeal Disease 57Ophthalmologic Disease 58Hematologic Disease 59Cardiac Disease 60Respiratory Disease 61Renal Disease 62Diabetes, Lipid Disorders, and Fat Redistribution Syndromes 63Gonadal, Adrenal, and Thyroid Disorders 64Gastrointestinal Disease 65Hepatic and Hepatobiliary Disease SECTION VIII: DRUG ADMINISTRATION AND INTERACTIONS 66Drug Administration and Interactions 67AIDS-Related Medications Appendix A: HIV/AIDS-Related Internet Resources Appendix B: Antiretroviral Adult Dosage Guidelines