Pericyte Biology in Different Organs (eBook)

Alexander Birbrair (Herausgeber)

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2019 | 1st ed. 2019
XI, 277 Seiten
Springer International Publishing (Verlag)
978-3-030-11093-2 (ISBN)

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The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research. 


This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, prostate, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology - Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs. 



Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC). 

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC). 

Chapter 1 -  Pericytes in the retina Chapter 2 - Pancreatic pericytes in glucose homeostasis and diabetesChapter 3 – Pericytes in the lungChapter 4 - Pericytes in the skeletal muscleChapter 5 – Pericytes in the gutChapter 6 – Pericytes in the bone marrow Chapter 7 – Cochlear Capillary PericytesChapter 8 - Pericytes in the placenta: role in placental development and homeostasis  Chapter 9 - Pericytes in the liver Chapter 10 - Pericytes in the Periodontal LigamentChapter 11 - Pericytes in the heartChapter 12 - Pericytes in the Umbilical CordChapter 13 - The pluripotent microvascular pericytes are the adult stem cells even in the testisIndex  

Erscheint lt. Verlag 1.4.2019
Reihe/Serie Advances in Experimental Medicine and Biology
Zusatzinfo XI, 277 p. 60 illus., 51 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte disease regulation • endothelial cells • homeostasis • pericytes • Stem Cell Biology
ISBN-10 3-030-11093-1 / 3030110931
ISBN-13 978-3-030-11093-2 / 9783030110932
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