Handbook of Diagnostic Biochemistry and Hematology in Normal Pregnancy

Preface. Acknowledgments. GESTATIONAL CHANGES IN NORMAL PREGNANCY. PHYSIOLOGICAL ADAPTATIONS IN NORMAL PREGNANCY. Physiological Adaptions in Normal Pregnancy. The Pregnancy Study. FLUIDS, ELECTROLYTES AND NITROGEN METABOLITES. Effect of Pregnancy on Fluids, Electrolytes and Nitrogen Metabolites. Sodium. Potassium. Chloride. Bicarbonate. Anion Gap. Urea. Creatinine. Uric Acid. CALCIUM, PHOSPHATE, MAGNESIUM. Effect of Pregnancy on Calcium and Phosphate. Total Calcium. Ionized Calcium. Phosphate. Effect of Pregnancy on Magnesium. Magnesium. GLUCOSE. Effect of Pregnancy on Carbohydrate Metabolism. Glucose. BILIRUBIN AND PLASMA ENZYMES. Effect of Pregnancy on Hepatic Function and Enzymes. Bilirubin (Unconjugated). Alanine Aminotransferase. Alkaline Phosphatase. Amylase. Aspartate Aminotransferase. Creatine Kinase. Gamma-Glutamyl Transferase. Lactate Dehydrogenase. PLASMA PROTEINS. Effect of Pregnancy on Plasma Proteins. Total Protein. Albumin. Colloid Osmotic Pressure. Alpha-1-Antitrypsin. Ceruloplasmin. Complement. Immunoglobulins. Prealbumin. Retinol-Binding Protein. Transferrin. a-FETOPROTEIN. a-Fetoprotein in Pregnancy. Screening for Neural Tube Defect and Down Syndrome. Other Maternal Serum Markers in Down Syndrome. LIPIDS AND LIPID-SOLUBLE VITAMINS. Effect of Pregnancy on Lipids and Lipid Soluble Vitamins. Cholesterol (Total). Cholesterol Fractions. Triglycerides. Effect of Pregnancy on Lipid Soluble Vitamins. Vitamin A. Vitamin E. WATER-SOLUBLE VITAMINS. Effect of Pregnancy on Vitamin Status. Erythrocyte Enzyme Assays for Vitamin Status Thiamine (B1), Riboflavin (B2), Pyridoxine (B6) Status. TRACE METALS. Effect of Pregnancy on Trace Elements (Zinc, Copper, Selenium). Zinc. Copper. Selenium. Glutathione Peroxidase. INDICES OF IRON METABOLISM. Effect of Pregnancy on Iron Metabolism. Iron. Iron Binding Capacity. Transferrin Saturation. Zinc Protoporphyrin. Ferritin. THYROID HORMONES AND CORTISOL. Effect of Pregnancy on Thyroid Hormone. Thyoxine. Triiodothyronine. Free Thyroxine. Thyroxine-Binding Globulin. Thyroid Stimulating Hormone. Effect of Pregnancy on Adrenal Function. Cortisol. GESTATIONAL CHANGES IN HEMATOLOGY. THE EFFECT OF PREGNANCY ON HEMATOLOGICAL INDICES. HEMATOLOGICAL INDICES. Hemoglobin. Erythrocyte Count. Hematocrit. Mean Corpuscular Volume. Mean Corpuscular Hemoglobin. Mean Corpuscular Hemoglobin Concentration. Red Cell Distribution Width. Leukocyte Count. Leukocyte Differential. Platelet Count. Mean Platelet Volume. COAGULATION INDICES. Prothrombin Time. Partial Thromboplastin Time. Fibrinogen. REFERENCE RANGES FOR NON-PREGNANT ADULT WOMEN. THE NON-PREGNANT CONTROL STUDY. LIFESTYLE FACTORS WHICH COULD MODIFY TEST RESULTS. REFERENCE RANGES FOR NON-PREGNANT ADULT WOMEN. Biochemistry Tests. Biochemistry Tests Contd. Biochemistry Tests Contd. Hematology Tests. STUDY PROTOCOL, MATERIALS AND METHODS. RECRUITMENT OF SUBJECTS. SPECIMEN COLLECTION AND PROCESSING PROTOCOLS. INSTRUMENTATION AND METHODS. Equipment and Methods. Quality Assurance and Proficiency Testing. Data Analysis. Index.