Target Organ Toxicology in Caenorhabditis elegans -  Dayong Wang

Target Organ Toxicology in Caenorhabditis elegans (eBook)

(Autor)

eBook Download: PDF
2019 | 1st ed. 2019
XIII, 337 Seiten
Springer Singapore (Verlag)
978-981-13-6010-7 (ISBN)
Systemvoraussetzungen
149,79 inkl. MwSt
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

This book introduces readers to intestinal and epidermal barriers, and to toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs in Caenorhabditis elegans. In addition, it discusses the protective responses of various organs and nematodes' avoidance behaviour with regard to environmental toxicants or stresses. The intestinal, epidermal, neuronal, and germline signalling pathways required for the regulation of toxicity of environmental toxicants or stresses are also introduced and discussed.

As a classic model animal with well-described genetic and developmental backgrounds, the nematode Caenorhabditis elegans has been successfully and widely used in both toxicity assessments and toxicological studies on various environmental toxicants and stresses. Once exposure to certain environmental toxicants has occurred, the toxicants can enter into the primary targeted organs (such as intestinal cells), and even be translocated into secondary targeted organs (such as reproductive organs and neurons). Based on related available data, this book provides a systematic understanding of target organ toxicology in C. elegans.



Dr. Dayong Wang is a professor at the Medical School, Southeast University, China. He obtained his Ph.D. from Peking University in 2001 and completed his post-doctoral training at the University of Toronto from 2002 to 2004. His research focuses on toxicology and pathology using Caenorhabditis elegans as a model animal, fields in which he has published more than 160 research articles.


This book introduces readers to intestinal and epidermal barriers, and to toxicity induction of environmental toxicants or stresses in the intestine, epidermis, neurons, muscle, and reproductive organs in Caenorhabditis elegans. In addition, it discusses the protective responses of various organs and nematodes' avoidance behaviour with regard to environmental toxicants or stresses. The intestinal, epidermal, neuronal, and germline signalling pathways required for the regulation of toxicity of environmental toxicants or stresses are also introduced and discussed. As a classic model animal with well-described genetic and developmental backgrounds, the nematode Caenorhabditis elegans has been successfully and widely used in both toxicity assessments and toxicological studies on various environmental toxicants and stresses. Once exposure to certain environmental toxicants has occurred, the toxicants can enter into the primary targeted organs (such as intestinal cells), and even be translocated into secondary targeted organs (such as reproductive organs and neurons). Based on related available data, this book provides a systematic understanding of target organ toxicology in C. elegans.

Dr. Dayong Wang is a professor at the Medical School, Southeast University, China. He obtained his Ph.D. from Peking University in 2001 and completed his post-doctoral training at the University of Toronto from 2002 to 2004. His research focuses on toxicology and pathology using Caenorhabditis elegans as a model animal, fields in which he has published more than 160 research articles.

Protective Responses of Different Organs to Environmental Toxicants or Stresses.- Avoidance Behaviour of Nematodes to Environmental Toxicants or Stresses.- Intestinal Barrier for Nematodes against Toxicity of Environmental Toxicants or Stresses.- Epidermal Barrier for Nematodes against Toxicity of Environmental Toxicants or Stresses.- Toxicity Induction in Intestine and Epidermis in Nematodes Exposed to Environmental Toxicants or Stresses.- Toxicity Induction in Neurons and Muscle in Nematodes Exposed to Environmental Toxicants or Stresses.- Reproductive Toxicity Induction in Nematodes Exposed to Environmental Toxicants or Stresses.- Intestinal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses.- Epidermal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses.- Neuronal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses.- Germline Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses.

Erscheint lt. Verlag 12.2.2019
Zusatzinfo XIII, 337 p. 232 illus., 175 illus. in color.
Verlagsort Singapore
Sprache englisch
Themenwelt Medizin / Pharmazie Gesundheitsfachberufe
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Zoologie
Schlagworte Caenorhabditis elegans • Environmental Stresses • Environmental toxicants • Model invertebrates • signalling pathways • Target organ toxicology
ISBN-10 981-13-6010-3 / 9811360103
ISBN-13 978-981-13-6010-7 / 9789811360107
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 25,4 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich