Precision Molecular Pathology of Myeloid Neoplasms

Chung-Che (Jeff) Chang, MD, PhDProfessor of PathologyUniversity of Central Florida;Medical Director, Hematology and Molecular Pathology LabsFlorida HospitalOrlando, Florida Robert S. Ohgami, MD, PhDAssistant Professor of PathologyAssociate Program Director for Anatomic PathologyDepartment of PathologyStanford UniversityStanford, California

Acute myeloid leukemia (AML) with recurrent cytogenetic abnormalities.- AML with characteristic molecular mutations: RUNX1, CEPA, NPM1, etc.- AML, NOS/AML with dysplasia-related changes/therapy-related myeloid neoplasm.- Myelodysplastic syndromes (MDS).- Chronic myelogenous leukemia (CML).- Polythesemia vera (PV).- Essential thrombocythemia (ET).- Primary myelofibrosis (PMF).- Mastocytosis.- Myeloproliferative neoplasms (MPN), rare types (Chronic eosinophilic leukemia, Chronic neutrophilic leukemia).- Atypical CML.- Chronic myelomonocytic leukemia (CMML).- Juvenile myelomonocytic leukemia (JMML).- Childhood MDS.- Familial AML/MPN/MDS.- Myeloid and lymphoid neoplasm with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1.