Genome Analysis and Human Health

  Dr. Leena Rawal is currently working as a Senior Scientist at the Department of Cytogenetics, Dr Lal PathLabs Limited, New Delhi. She was awarded her PhD degree in Molecular Genetics by the University of Delhi in 2014, and subsequently worked as a Post-doctoral fellow at the National Institute of Immunology, New Delhi. She has since worked as a Senior Scientist and Head of the Molecular Diagnostics and Research Division at a renowned pharmacogenomics-based organization. Dr. Rawal has published several original papers in international peer-reviewed journals like Plos ONE, BMC Genomics, DNA and Cell Biology, Gene and the Journal of Molecular Structure and Dynamics.  Her expertise lies in the area of Human and Animal Genetics, Proteomics, Cytogenetics and Bioinformatics. She presented her work at the 34th Annual Lorne Genome Conference in Melbourne, Australia in 2013. She has also been a reviewer for Plos ONE.   Professor Sher Ali is aninternationally respected scientist in the field of genomics and molecular genetics. He received his PhD from the University of Delhi in 1981 and subsequently worked as an Alexander von Humboldt Fellow at the Max Planck Institute of Immunobiology in Freiburg, Germany. He retired from the National Institute of Immunology (NII), New Delhi in 2015 after serving the institute for more than 25 years. At the NII, he was head of the Molecular Genetics Laboratory. Currently, he is working as a Professor at the Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi.  His research interests include Genome Analysis, Molecular Human and Animal Genetics, Germ Line Genetics, Toxicogenomics, DNA Diagnosis and Cancer Genetics. His outstanding research has attracted attention from various pharmaceutical companies. Dr. Ali has published over 100 peer-reviewed papers in reputed international journals. He is a member of all three Academies of Sciences in India namely the Indian Academy of Sciences, National Academy of Sciences and Indian National Science Academy, and has been a reviewer and editorial board member for various prestigious journals such as Molecular and Cellular Probes; American Journal of Cancer Genetics, Scientific Reports etc. He is the recipient of several national and international awards, including most recently an Alexander von Humboldt-Stiftung Fellowship, Bonn, Germany and the N.K. Iyengar Memorial Gold Medal.

Chapter 1. Genetic and epigenetic regulation of autophagy in cancer.- Chapter 2. Genome Analysis and Cancer.- Chapter 3. Cancer Genomics and Precision Medicine: a way towards early diagnosis and effective cancer treatment.- Chapter 4. Genetics of Liver Diseases.- Chapter 5.  Implication of Pre-replication Complex Proteins in Human Disease.- Chapter 6. Non-muscle myosin II motor proteins in health and diseases.- Chapter 7. Bioinformatics Databases: Implications in Human Health.- Chapter 8. Genomics of the Human Y chromosome: Applications and Implications.- Chapter 9. Human Microbiome: Implications on health and diseases.