General and Applied Toxicology

Volume I General aspects. Part 1 Introductory and basic material: fundamentals of toxicology, B. Ballantyne et al; statistics for toxicology, P.N. Lee; principles of testing for acute toxic effects, C. Rhodes et al; biotransformation of xenobiotics, J. Timbrell; toxicokinetics, A.G. Renwick; physiologically-based pharmacokinetic modeling, Hon-Wing Leung; biochemical mechanisms of toxicology, J. Caldwell; alternatives to in vivo studies in toxicology, S.C. Gad; acute non-specific toxicity, J.A. Henry and S.L. Cassidy; information resources for toxicology, J. Deschamps and Morgan. Part 2 Techniques in toxicity: design of toxicology studies, A. Paine; pathological techniques in toxicology, P. Greaves; haematology in toxicology studies, D. Woodman and J. Fuller; clinical chemistry in toxicology studies, M. Stonard and Evans; antidotal studies, N. Bateman and T.C. Marrs; quality assurance in toxicology studies, T.R. Stiles; hazards in the toxicology laboratory, B. Ballantyne; evaluation of toxicity in human subjects, P.N. Bennett. Part 3 Toxicity by routes: parental toxicity, D. Walker peroral toxicity, T.R. Tyler; percutaneous toxicity, Hon-Wing Leung; inhalation toxicity, P. Hext and I.P. Bennett. Volume II Organ and special toxicity - applied toxicology. Part 1 Target organ toxicity: neurotoxicity, J.N. LeFauconnier; peripheral sensory irritation, B. Ballantyne nephrotoxicity, B.A. Lock; systemic pulmonary toxicity, J.P. Kehrer; pulmonary hypersensitivity reactions, H.C. Lewinsohn and H.D. Burleigh-Flayer ophthalmic toxicology, B. Ballantyne; cardiovascular toxicity, S.I. Baskin heptotoxicity, P. Grasso and R.H. Hinton; toxicity of the pancreas, J.M. Braganza; toxicology of skeletal muscle, K.E. Misulis et al; toxicology of bone, A.G.B. Lansdowne; cutaneous toxicity, S.J. Hermansky; ototoxicity, Forge and E.S. Harper, toxicology of the adrenal, thyroid and endocrine pancreas, J.A. Thomas; immunotoxicology, K. Miller and C. Neredith; haematotoxicology, J. Amess. Part 2 Special toxicology: mutagenicity, A. Tweats; cytogenetics, D. Anderson; chemical carcinogenesis (genotoxic), D.B. McGregor; chemical carcinogenesis (epigenetic), C. Berry; Reproductive toxicology, J.N. Ratcliffe and F. Sullivan; developmental toxicology, R.W. Tyl; neonatal toxicology, S. Kacew. Part 3 Regulatory tocicology: overview of regulatory agencies, G. Diggle; regulation of drugs in Europe and the United Kingdom, R.D. Mann; regulation of drugs on the North American continent, M.B. Vernoy; regulation of veterinary product in Europe and the United Kingdom, K. Woodward; regulation of veterinary products in the United States, K. Woodward; regulation of industrial chemicals and pesticides in Europe and the United Kingdom, R. Fielder and Martin; regulation of food additives and food contact materials on the North American continent, M.B. Vernoy. Part 4 Toxicology in special situations: pharmaceutical toxicology, P.F. D'Arcy; medical devices, Adams. Part contents.