Gene Regulation

Examines the biology of antisense oligodeoxynucleotides, RNA and ribozymes, and explores their potential therapeutic applications, particularly for inhibition of viral replication and cancer gene expression. Close attention is also given to drug approval.

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This volume examines the biology of antisense oligodeoxynucleotides, RNA, and ribozymes and explores their potential therapeutic applications, particularly for inhibition of viral replication and cancer gene expression. Leading international experts from academic institutions and industry describe approaches to development of pharmaceuticals using antisense ribozymes, oligonucleosides, and RNA. Close attention is also given to drug approval and other practical issues involved in introducing these agents into clinical practice.