Principles and Practice of Transplant Infectious Diseases

Amar Safdar, MD Clinical Associate Professor of Medicine Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine El Paso, TX, USA

Chapter 1   



Infections in Transplantation:  Introduction and Overview



Amar Safdar



 



Chapter 2     



Infections in Heart, Lung, and Heart-Lung Transplantation



Andrés F. Henao-Martínez and José G. Montoya  



 



Chapter 3   



Infections in Liver Transplantation



B. Sharmila Mohanraj, Amol S. Rangnekar, and Joseph G. Timpone, Jr



 



Chapter 4   



Infections in Kidney and Pancreas Transplantation



Megan K. Morales, Matthew Cooper, Peter Abrams, and Joseph G. Timpone, Jr



 



Chapter 5   



Infections in Intestinal and Multivisceral Transplantation



Raffaele Girlanda, Joseph G. Timpone, Jr, Kevin M. Soriano, and Thomas M. Fishbein



 



 



Chapter 6   



Infections in Limbs, Integuments, and Face Transplantation



Justin M. Broyles and Chad R. Gordon



 



Chapter 7   



Principles of Hematopoietic Stem Cell Transplantation



Michelle Limei Poon, Richard E. Champlin, and Partow Kebriaei



 



Chapter 8   



Infections in Pediatric Transplant Recipients



Aspasia Katragkou, Lucy O’Connor, Emmanuel Roilides, and Thomas J. Walsh



 



Chapter 9   



Febrile Neutropenia in Transplant Recipients



Lior Nesher and Kenneth V. I. Rolston



 



Chapter 10   



Cytopenias in Transplant Patients



Maura Barry, Sunandana Chandra, and Kenneth B. Hymes



 



Chapter 11   



Infections in Allogeneic Stem Cell Transplantation



Marcus R. Pereira, Stephanie M. Pouch, and Brian Scully



 



Chapter 12   



Complications Arising from Preparatory Conditioning Regimens for Stem Cell Transplantation



Jasmine Zain and Merav Bar



 



Chapter 13   



Intravascular Catheter and Implantable Device Infections in Transplant Patients



Nasia Safdar, Cybele Lara R. Abad, and Dennis G. Maki



 



Chapter 14   



Surgical Site Infections: Wound and Stump Infections



Nasia Safdar, Sara A. M. Zerbel, and Elizabeth Ann Misch



 



Chapter 15   



Endovascular Infections and Endocarditis



Walter Zingg and Didier Pittet



 



Chapter 16   



Gastrointestinal Infections and Clostridium difficile Infection



Stephen Harold and Herbert L. DuPont



 



Chapter 17   



Hepatobiliary Tract Infections



Jonathan Merola, Robert M. Mocharla, Alexander Z. Jow, Samuel H. Sigal, and Amar Safdar



 



Chapter 18   



Ocular Infections in Transplant Patients



Ann-Marie Lobo, Lucia Sobrin, and Marlene L. Durand



 



Chapter 19   



Intracranial, Spinal, and Paraspinal Infections in the Transplant Recipient



Matthew W. McCarthy, Axel Rosengart and Thomas J. Walsh



 



Chapter 20   



Respiratory Tract Infections: Sinusitis, Bronchitis, and Pneumonia



Benjamin A. Miko, Marcus R. Pereira, and Amar Safdar



 



Chapter 21   



Respiratory Tract Diseases That May Be Mistaken For Infection                             



Robert M. Kotloff, Burton F. Dickey, and Nicholas Vander Els



 



Chapter 22   



Skin and Soft Tissue Infection in Transplant Recipients



Robert G. Micheletti and Carrie L. Kovarik



 



Chapter 23   



Cutaneous Lesions that Mimic Infection in Transplant Patients



Ana Ciurea and Sharon Hymes



 



Chapter 24   



Staphylococcus, Streptococcus, and Enterococcus



Amar Safdar and Donald Armstrong



 



Chapter 25   



Enterobacteriaceae in Transplantation



Kathryn Whitaker, Valerie Cluzet, and Emily A. Blumberg



 



Chapter 26  



Pseudomonas, Stenotrophomonas, Acinetobacter, and Other Non-Fermentative Gram-Negative Bacteria & Medically Important Anaerobic Bacteria in Transplant Recipients



Kenneth V.I. Rolston and Amar Safdar



 



Chapter 27   



Nocardiosis and Actinomycosis



Heather E. Clauss and Bennett Lorber



 



Chapter 28   



Listeriosis



Heather E. Clauss and Bennett Lorber



 



Chapter 29   



Tuberculosis



Cynthia Portal-Celhay and Jennifer A. Philips



 



Chapter 30   



Nontuberculous Mycobacterial Disease in Transplant Recipients



Julie V. Philley, Amar Safdar, and Charles L. Daley



 



 



 



Chapter 31   



Invasive Fungal Disease in the Transplant Population: An Overview



Jennifer L. Saullo,  John R. Perfect, and Barbara D. Alexander



 



Chapter 32   



Candida Infections in Hematopoietic and Solid Organ Transplant Recipients



Alison G. Freifeld and Carol A. Kauffman



 



Chapter 33   



Aspergillosis



Michael J. Satlin, Samantha E. Jacobs, and Thomas J. Walsh



 



Chapter 34   



Mucormycosis



Brad Spellberg and Johan Maertens



 



Chapter 35  



Cryptococcus Infections in Transplant Recipients



Raymund R. Razonable and Pearlie P. Chong



 



Chapter 36   



Histoplasmosis, Coccidioidomycosis and Diseases due to Other Endemic Fungi in Transplant Recipients



Pascalis Vergidis, Chadi A. Hage, and L. Joseph Wheat



 



Chapter 37   



Cytomegalovirus



Amar Safdar and Donald Armstrong



 



Chapter 38   



Epstein-Barr Virus Infection and Post-Transplant Lymphoproliferative Disease



Benjamin E. Gewurz, Amy Sievers, David M.Weinstock, Sheila Mitsuma and Amar Safdar



 



Chapter 39   



Herpes Simplex Viruses 1 and 2, Varicella Zoster Virus and Human Herpes Viruses 6, 7 and 8 in Transplant Recipients



Raymund R. Razonable*



 



Chapter 40   



Respiratory Viral Infections in Transplant Recipients



Catherine Liu, Dora Y. Ho, and Michael Boeckh



 



Chapter 41   



Hepatitis A, B, C



Jonathan Merola, Alexander Z. Jow, and Samuel H. Sigal



 



Chapter 42   



Enterovirus Infection in Immunocompromised Hosts



Joanna Schaenman, Dora Y. Ho, Lindsey R. Baden, and Amar Safdar



 



Chapter 43   



Parvovirus B19 



Morgan Hakki and Lynne Strasfeld



 



Chapter 44   



West Nile Virus in Immunocompromised Hosts 



Dora Y. Ho, Joanna M.D. Schaenman, and Lindsey R. Baden



 



Chapter 45   



Rare and Emerging Viral Infections in the Transplant Population



Susanna K. Tan, Jesse J. Waggoner, and Stan Deresinski



 



Chapter 46   



Parasitic Infections in Transplant Recipients: Toxoplasmosis, Strongyloidiasis and Other Parasites



Brian G. Blackburn and José G. Montoya



 



Chapter 47   



Impacts and Challenges of Advanced Diagnostic Assays for Transplant Infectious Diseases



N. Esther Babady, Yeon Joo Lee, Genovefa Papanicolaou, and Yi-Wei Tang



 



Chapter 48   



Diagnosis of Systemic Fungal Diseases



Simon F. Dufresne, Kieren A. Marr and Shmuel Shoham



 



Chapter 49   



Viral Diagnostics



Robin K. Avery and Belinda Yen-Lieberman



 



Chapter 50   



Antibiotic Consideration in Transplant Recipients



Jerry Altshuler, Samuel L. Aitken, Melanie Maslow, John Papadopoulos, and Amar Safdar



 



Chapter 51   



Pharmacokinetics and Pharmacodynamics of Antibiotics in Transplant Patients



Kelly E. Schoeppler, Scott W. Mueller, and Gerard R. Barber



 



Chapter 52   



Antifungal Consideration for Transplant Recipients



Yanina Dubrovskaya, Man Yee Merl, David S. Perlin, and Amar Safdar



 



Chapter 53   



Immunomodulatory Properties of Antifungal Agents on Immune Functions of the Host



Maria Simitsopoulou and Emmanuel Roilides



 



Chapter 54   



Antiviral Consideration for Transplantation Including Drug Resistance



Sunwen Chou and Nell S. Lurain



 



Chapter 55   



Pharmacokinetics and Pharmacodynamics of Antiviral Drugs in Special Population



Marco R. Scipione* and John Papadopoulos



 



Chapter 56   



Anti-Mycobacterial Consideration in Transplantation Including Drug Non-Susceptibility and Resistance: Tuberculosis and Nontuberculous Mycobacterial Disease



Julie V. Philley and David E. Griffith



 



 



 



Chapter 57   



Adaptive Immunotherapy for Opportunistic Infections



Aspasia Katragkou, Thomas J. Walsh, and Emmanuel Roilides 



 



Chapter 58   



Immunotherapy for Invasive Mold Disease in Transplant Patients – Dendritic Cell Immunotherapy, Interferon-gamma, Recombinant Myeloid Growth Factors, and Healthy Donor Granulocyte Transfusions



William K. Decker, Matthew M. Halpert, Vanaja Konduri, Dan Liang, Christopher N. Hampton, and Amar Safdar



 



Chapter 59   



Antimicrobial Stewardship: Considerations for a Transplant Center



Susan K. Seo and Graeme N. Forrest



 



Chapter 60   



The Use of Palliative Care in Organ Transplant Patients and End of Life Issues



Jenny S. Ayala and Joseph Lowy



 



Chapter 61   



Infection Control Strategies in Transplant Populations



Scott Cutro, Michael Phillips, and Harold W. Horowitz



 



Chapter 62   



Travel and Transplantation 



Camille Nelson Kotton and José G. Montoya



 



Chapter 63   



Vaccination in Organ Transplant



Lara Danziger-Isakov and Camille Nelson Kotton



 



Chapter 64   



Prevention of Fungal Disease



Shirish Huprikar and John R. Wingard



 



Chapter 65   



Antimicrobial Drug Prophylaxis: Challenges and Controversies



Gaurav Trikha, Marcio Nucci, John R. Wingard and Amar Safdar