Rare Kidney Tumors (eBook)

Dr. Gabriel G. Malouf, is professor of medical oncology in Strasbourg University and researcher at the Institute of Genetics and Molecular and Cellular Biology (IGBMC). A staff member of the department of medical oncology, Dr Malouf’s clinical and translational research focus on genitourinary malignancies. Doctor Malouf earned a medical degree at the University of Paris Descartes (2012). After completing a residency program in medical oncology, Dr Malouf was postdoctoral postdoctoral follow at MD Anderson cancer center. After returning to Paris, Dr Malouf earned a PhD in cancer epigenetics (2014). Dr Malouf developed an expertise in rare kidney cancers, especially translocation renal cell carcinoma, medullary renal cell carcinomas and collecting duct carcinomas. Dr Malouf published more than 50 original papers in high-impact journals such as Clinical Cancer Research, Cancer Research and Genome Biology. In addition, Dr Malouf serve as faculty member for main meetings such as ASCO Genitourinary and EMUC (European Multidisciplinary Meeting on Urological Cancers) meetings. Dr Malouf is the coordinator of the research programs at the medical oncology department. His current focus is to develop a translational research program focusing on deciphering genetic and epigenetic aberrations of rare genitourinary malignancies. Dr. Nizar M. Tannir, is Professor and Deputy Chair of the Department of Genitourinary Medical Oncology at MD Anderson Cancer Center, and is a clinical investigator with expertise in trial design. Dr. Tannir has conducted numerous clinical trials in renal cell carcinoma (RCC), and is an expert on rare kidney cancers, particularly, translocation RCC (Xp11.2) and renal medullary carcinoma (RMC). He co-chairs a think-tank on RMC, bringing together world experts from different fields to accelerate discovery and novel therapeutics for this devastating orphan cancer. Dr. Tannir has authored more than 150 original manuscripts and several book chapters. He is editor of Renal Cell Carcinoma, a book published by Oxford University Press in 2014. Dr. Tannir co-chairs a yearly urological oncology symposium at MDACC, and serves on the scientific and medical advisory board of the Kidney Cancer Association. Dr. Tannir’s research is focused on deciphering the molecular underpinnings of RMC and Xp11.2. He is Principal Investigator of several clinical trials in advanced clear-cell and non-clear cell RCC, including rare variants, with emphasis on identification of prognostic and predictive biomarkers. Dr. Tannir was voted Teacher of The Year four times, and received numerous awards including the Gerald P. Bodey Award for Excellence in Education, the Waun Ki Hong Award for Leadership in Education, and the Melvin L. Samuels Award for Excellence in Patient Care.

Introduction.- Hereditary RCC Syndromes.- Wilms Tumor.- Renal Cell Carcinomas in Children.- Chromophobe Renal Cell Carcinomas.- Papillary Renal Cell Carcinoma.- Renal Medullary Carcinomas.- Collecting Duct Carcinomas.- Translocation Renal Cell Carcinomas.- Angiomylipoma.- Sarcomatoid and Rhabdoid Renal Cell Carcinoma.- Conclusion.