Principles and Practice of Assisted Reproductive Technology

Kamini A Rao MBBS DGO MCh FRCOG FNAMS FICOG PGDMLE Medical Director, Milann Group of Fertility Centres, Bengaluru, Karnataka, India

Volume 1 Infertility





Section 1: Anatomy and Physiology


Chapter 1. Anatomy of Reproductive System
Chapter 2. Regulation and Physiology of Menstrual Cycle
Chapter 3. Oogenesis and Folliculogenesis
Chapter 4. Spermatogenesis
Chapter 5. Fertilization and Embryogenesis
Chapter 6. Implantation
Chapter 7. Embryo-Endometrial Crosstalk and Endometrial Receptivity



Section 2: Reproductive Endocrinology


Chapter 8. Synthesis and Metabolism of Steroid Hormones
Chapter 9. Puberty and Aberrations
Chapter 10. Amenorrhea
Chapter 11. Endocrine Disorders Affecting Reproduction
Chapter 12. Hirsutism
Chapter 13. Luteal Phase Defect
Chapter 14. Anovulation





 





Section 3: Combined Topics


Chapter 15. Declining Fertility
Chapter 16. Evaluation of Infertility
Chapter 17. Immunology and Infertility
Chapter 18. Cytogenetics and Infertility
Chapter 19. Obesity and Infertility
Chapter 20. Unexplained Infertility
Chapter 21. Fertility Preservation
Chapter 22. Counseling in Infertility





 





Section 4: Male Infertility


Chapter 23. Etiopathogenesis of Male Infertility
Chapter 24. Clinical and Endocrinological Evaluation of Infertile Male
Chapter 25. Male Sexual Dysfuntion
Chapter 26. Ultrasound in Male Infertility
Chapter 27. Medical Management of Male Infertility
Chapter 28. Azoospermia: Evaluation and Management





 





Section 5: Female Factor Infertility


Chapter 29. Uterine Factors in Infertility
Chapter 30. Tubal Factors in Infertility
Chapter 31. Infections and Infertility
Chapter 32. Tuberculosis and Infertility
Chapter 33. Ultrasound in Female Infertility
Chapter 34. Transvaginal Ultrasound and Doppler in Infertility
Chapter 35. Polycystic Ovary Syndrome
Chapter 36. Assessment of Ovarian Reserve
Chapter 37. Endometriosis
Chapter 38. Endoscopy in Infertility
Chapter 39. Fertility Enhancing Endoscopic Surgeries





 





Section 6: Ovarian Stimulation


Chapter 40. Drugs for Ovarian Stimulation
Chapter 41. Ovulation Induction and Ovarian Stimulation Protocols
Chapter 42. Role of Adjuvants in Ovarian Stimulation
Chapter 43. Gonadotropin-releasing Hormone Analogs
Chapter 44. Monitoring of Ovarian Stimulation
Chapter 45. Ovulation Trigger
Chapter 46. Individualized Controlled Ovarian Stimulation
Chapter 47. IVF Lite
Chapter 48. Role of LH in Ovarian Stimulation





 





Section 7: Intrauterine Insemination


Chapter 49. Intrauterine Insemination
Chapter 50. Optimizing Success in Intrauterine Insemination





 





Section 8: Assisted Reproductive Techniques


Chapter 51. Anesthesia in Assisted Reproductive Techniques
Chapter 52. Oocyte Retrieval
Chapter 53. Embryo Transfer
Chapter 54. Troubleshooting in ART
Chapter 55. Luteal Phase Support





 





Section 9: Dilemmas in ART


Chapter 56. Poor Responders
Chapter 57. Recurrent Implantation Failure
Chapter 58. Empty Follicle Syndrome
Chapter 59. Role of Aneuploidy Screening in Preimplantation Embryos
Chapter 60. Epigenetics and ART





 





Section 10: Complications of ART


Chapter 61. Ovarian Hyperstimulation Syndrome
Chapter 62. Ectopic Pregnancy
Chapter 63. Multiple Order Birth





 





Section 11: Third Party Reproduction


Chapter 64. Oocyte and Sperm Donation
Chapter 65. Surrogacy in Assisted Reproductive Technology
Chapter 66. ART Guidelines
Chapter 67. Adoption





 





Section 12: Miscellaneous


Chapter 68. Batch IVF
Chapter 69. Frozen Embryo Transfer
Chapter 70. Evidence-based Practice in Reproduction Medicine
Chapter 71. Ethical, Legal and Social Issues of Modern ART Practice
Chapter 72. Total Quality Management
Chapter 73. Auditing of Clinical Outcomes
Chapter 74. Periconceptional Challenges and Modifiable Risk Factors: Evidence to Practice





 





Section 13: Outcome Following ART


Chapter 75. Maternal and Fetal Outcome Following ART
Chapter 76. Early Pregnancy Scan
Chapter 77. Recurrent Pregnancy Loss





 





Section 14: Future Clinical Applications


Chapter 78. Endometrial Stem Cells and Reproduction
Chapter 79. Recent Trends in ART
Chapter 80. Uterine Transplant
Chapter 81. Ovarian Transplant
Chapter 82. Novel Ways of Creating Vagina
Chapter 83. Genitoplasty
Chapter 84. Emergencies in Infertility
Chapter 85. Fetal Reduction





Index: Outcome Following ART



Volume 2 Laboratory Aspects of IVF and Andrology





Section 1: Andrology


Chapter 1. Semen Analysis in 21st Century Medicine: A Paradigm Shift
Chapter 2. Sperm Function Tests
Chapter 3. Selection of Sperm
Chapter 4. Sperm Chromatin Assessment
Chapter 5. Sperm Preparation Techniques
Chapter 6. Semen Banking





 





Section 2: Embryology


Chapter 7. History of In Vitro Fertilization
Chapter 8. In Vitro Fertilization and Embryo Transfer
Chapter 9. Intracytoplasmic Sperm Injection
Chapter 10. Analysis of Fertilization
Chapter 11. Morphological Assessment of Oocyte and Embryo
Chapter 12. Blastocyst Culture and Transfer
Chapter 13. Cryopreservation of Oocytes
Chapter 14. Embryo Cryopreservation





 





Section 3: Advances in Assisted Reproductive Technologies


Chapter 15. Assisted Hatching in ART
Chapter 16. Preimplantation Genetic Screening and Diagnosis: Laboratory Aspects
Chapter 17. In Vitro Maturation of Oocytes: A Practical Approach
Chapter 18. Ovarian Cortex Cryopreservation: The Current Perspective
Chapter 19. Embryoscope
Chapter 20. Polarization Microscopy and its Clinical Applications
Chapter 21. Omics and ART
Chapter 22. IMSI, PICSI and its Clinical Significance
Chapter 23. Microfluidics in ART





 





Section 4: Ethical and Legal Issues


Chapter 24. Quality Management in Assisted Reproductive Technology Clinics





 





Section 5: Laboratory Management


Chapter 25. Setting-up an ART Laboratory
Chapter 26. Quality Control in IVF Laboratory
Chapter 27. Embryo Culture Systems
Chapter 28. Micromanipulators
Chapter 29. Troubleshooting in the IVF Laboratory: Challenging Case Scenarios





Index



Volume 3 Atlas of Human Embryology





Chapter 1. Oocyte Cumulus Complex Evaluation
Chapter 2. Oocyte Nuclear Maturity Evaluation
Chapter 3. Oocyte Dysmorphisms
Chapter 4. The Sperm
Chapter 5. Normal Embryo Development
Chapter 6. Embryo Scoring
Chapter 7. In Vitro Fertilization/Intracytoplasmic Sperm Injection
Chapter 8. Advanced Techniques
Chapter 9. Cryopreservation
Chapter 10. Assisted Reproductive Technology Laboratory Setting
Chapter 11. Embryo Biopsy


Index