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Gamete and Embryo Micromanipulation in Human Reproduction
Hodder Arnold (Verlag)
978-0-340-57370-9 (ISBN)
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One in ten couples in the UK experience problems with conceiving a child. Assisted reproduction or in vitro fertilization (IVF) techniques have been developed over the last 13 years to provide help for some of these sub-fertile couples. More recently, micromanipulation techniques have been used successfully to achieve fertilization in patients not helped by normal IVF. This book brings together the most recent advances in micromanipulation techniques from internationally renowned IVF centres and discusses the technical, legal and ethical considerations of work on the human embryo.
Part 1 Introduction: historical overview of the use of micromanipulation. Part 2 Gamete micromanipulation: preparative techniques in micromanipulation; experience with subzonal insemination in mouse and cow; techniques for the preparation of spermatozoa and the need for capacitation and the acrosome reaction. Part 3 Subzonal insemination - SUZI: the need for micro-assisted fertilization in human reproduction; sperm micro-injection and microfertilization; subzonal insemination and zona breaching techniques for assisted fertilization. Part 4 Partial zona pellucida dissection (PZD): microsurgical fertilization and zona pellucida micromanipulation; partial zona pellucida dissection as an assisted fertilization technique in subfertile males; preliminary studies with partial zona dissection and clinical pregnancies. Part 5 New approaches to micro-assisted fertilization: from conventional to laser micromanipulation of gametes; new advances in micromanipulation - applications for treatment of the severe male factor patient; micro-assisted reproduction - is it the treatment of choice after fertilization failure?. Part 6 Embryo micromanipulation: prelude to pre-implantation diagnoisis in the human; embryo microsurgery for large animals; an overview of pre-implantation diagnosis; pre-implantation diagnoisis - strategies for embryo biopsy and genetic analysis; pre-implantation cytogenetic diagnosis; "In vitro" culture of biopsied blastomeres and diagnosis of aneuploidy; gamete and embryo micromanipulation in human reproduction - perspicacity or opacity? Part 7 Legal and ethical debate: legal implications raised by micromanipulation techniques; ethics of gamete and embryo micromanipulation in human reproduction.
Erscheint lt. Verlag | 1.7.1993 |
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Zusatzinfo | line drawings, half-tones |
Verlagsort | London |
Sprache | englisch |
Maße | 253 x 197 mm |
Gewicht | 714 g |
Themenwelt | Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie |
ISBN-10 | 0-340-57370-8 / 0340573708 |
ISBN-13 | 978-0-340-57370-9 / 9780340573709 |
Zustand | Neuware |
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