Fundamental Immunology

Part 1 Introduction: the immune system - an introduction, William E. Paul; the history of immunology, Arthur M. Silverstein. Part 2 The organization and development of the immune system: b lymphocytes, Paul W. Kincade and Jeffrey M. Gimble; t lymphocytes and the thymus, Jonathan Sprent; macrophages, antigen-presenting cells and the phenomena of antigen handling and presentation, Emil R. Unanue; lymphoid tissues and organs, Louis Picker and Mark H. Siegelman; evolution of the immune system, Louis Du Pasquier. Part 3 Antigens, antibodies and receptors: immunogenicity and antigen structures, Jay A. Berzofsky and Ira J. Berkower; immunoglobulins - structure and function, Leon Carayannopoulos and J. Donald Capra; immunoglobulins - molecular genetics, Edward E. Max; t lymphocyte antigen receptors, Stephen M. Hendrick; antigen-antibody interactions and monoclonal antibodies, Jay A. Berzofsky et al. Part 4 Lymphocyte activation, proliferation and differentiation: t lymphocyte activation, Arthur Weiss; b lymphocyte activation, Anthony L. DeFranco; accessory molecules, Ethan M. Shevach. Part 5 The major histocompatibility complex: the major histocompatibility complex, Ted H. Hansen et al; antigen processing and presentation, Ronald N. Germain. Part 6 Regulation of the immune response: immunologic tolerance, Ronald H. Schwartz; t-cell mediated regulation - help and suppression, Frank W. Fitch et al; t-cell-derived cytokines and their receptors, Maureen Howard et al; macrophage-derived mediators, Scott K. Durum and Joost J. Oppenheim; immunoglobulin class switching, Fred D. Finkelman and Clifford M. Snapper; som atic mutation and affinity maturation, Patricia J. Gearhart; idiotypic networks, John F. Kearney; immunosuppression, Nolan H. Sigal and Francis J. Dumont. Part 7 Effector mechanism of immunity: the complement system, M. Kathryn Liszewski and John P. Atkinson; phagocytosis, Steven Greenberg and Samuel C. Silverstein; the functions and mechanisms of action of cytolytic lymphocytes, Gideon Berke; inflammation, John I. Gallin. Part 8 Immunologic mechanisms in disease: autoimmunity and autoimmune disorder, Robert S. Schwartz; transplantation and graft rejection, Hugh Auchincloss, Jr and David H. Sachs; tumor immunology, Hans Schreiber; immunoparasitology, Phillip Scott and F. Alan Sher; immunity to viruses, Rolf M. Zinkernagel; immunity to intracellular bacteria, Stefan H.E. Kaufmann; immunity to extracellular bacteria, Emil C. Gotschlich; vaccines, Gordon L. Ada; primary immunodeficiency diseases, Rebecca H. Buckley; immunology of HIV infection, Anthony S. Fauci and Zeda F. Rosenberg ; allergy and mechanisms of hypersensitivity, Marshall S. Plaut and Eugene M. Zimmerman.