Immunotherapy
Springer International Publishing (Verlag)
978-3-030-02504-5 (ISBN)
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This new edition will inform readers on the latest in biomarker development to identify patients who are more likely to respond, and strategies to overcome the challenges of immune-related adverse events. In addition, the authors recognize that including the missing patient voice in clinical trials and longitudinal assessment of symptom reports may help to identify early indicators of response or toxicity. Thus, the book includes a chapter on patient-reported outcomes in patients treated with immunotherapies. The authors believe that acquiring this knowledge will help health care professionals make informed treatment decisions.
Edited by two renowned experts in the field, the book's chapters are written by a diverse cast of experts conducting cutting-edge research, providing the reader with the most up-to-date science.
Dr. Aung Naing is an Associate Professor in the Department of Investigational Cancer Therapeutics at MD Anderson Cancer Center and is also a Principal Investigator on immunotherapy-based clinical trials. Focusing on clinical translation of basic immunobiology, Dr. Naing's research interests are (1) identifying immunologic biomarkers of response to immunotherapy, (2) predicting primary and secondary resistance to immunotherapy, (3) developing immunotherapeutic strategies to overcome resistance, and (4) identifying predictive markers for immune-related adverse events (irAE) associated with immunotherapies. Joud Hajjar is an Assistant Professor of Allergy and Immunology and serves as the service chief of adult allergy and immunology at Texas Children's Hospital. She is a member of the Basic and Clinical Immunology Interest group at the American Academy of Allergy Asthma and Immunology, and the Early Career Immunologist Committee at the Clinical Immunology Society. Dr. Hajjar serves as a reviewer for the Journal of Clinical Immunology, Journal of General Internal Medicine and Allergy and Asthma Proceedings. She has received travel awards to present her research at the Clinical Immunology Society, American Academy of Allergy, Asthma and Immunology, and the American College of Allergy, Asthma and Immunology national meetings. Dr. Hajjar's research interests are in primary immunodeficiency disorders, and cancer immunotherapy.
1. Overview of Basic Immunology and Translational Relevance for Clinical Investigators
2. Immunotherapy for Melanoma
3. Immunotherapy in Lung Cancer: A New Age in cancer treatment
4. Update on Immunotherapy in AML and MDS: Monoclonal Antibodies and Checkpoint Inhibitors Paving the Road for Clinical Practice
5. Skin Reactions to Immune Checkpoint Inhibitors
6. Immune-related Adverse Events: Pneumonitis
7. Immune checkpoint inhibitors-induced colitis
8. Immune checkpoint inhibitors-induced hepatitis
9. Symptoms as patient-reported outcomes in cancer patients undergoing immunotherapies
Erscheinungsdatum | 30.12.2018 |
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Reihe/Serie | Advances in Experimental Medicine and Biology ; 995 |
Zusatzinfo | VIII, 182 p. 503 illus., 17 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Maße | 155 x 235 mm |
Gewicht | 445 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Studium | |
Schlagworte | IL-10 • ImmunoOncology • immunotherapy • Translational cancer immunology • Vaccine |
ISBN-10 | 3-030-02504-7 / 3030025047 |
ISBN-13 | 978-3-030-02504-5 / 9783030025045 |
Zustand | Neuware |
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