Targeted Therapy of Colorectal Cancer Subtypes
Springer International Publishing (Verlag)
978-3-030-02770-4 (ISBN)
The collection of chapters in this volume address the biology of specific CRC subtypes and how these may be targeted to improve precision therapy and clinical benefit for the patients.
Peter Jordan is the President of the National Institute of Health Dr. Ricardo Jorge Scientific Committee. His research group is dedicated to the study of cancer's molecular and cellular biology.
Preface.- Colorectal Cancer Subtypes- the current portrait.- Targeting colon cancers with mutated BRAF and microsatellite instability.- Targeting KRAS mutant CMS3 subtype by metabolic inhibitors.- Targeting the PI3K Signalling as a Therapeutic Strategy in Colorectal Cancer.- Targeting PTEN in colorectal cancers.- Wnt signalling-targeted therapy in the CMS2 tumour subtype: a new paradigm in CRC treatment?- Impact of the microenvironment on tumour budding in colorectal cancer.- Anti-EGFR Therapy to treat metastatic colorectal cancer: not for all.- miRNAs as modulators of EGFR therapy in colorectal cancer.- Index.
Erscheinungsdatum | 07.02.2019 |
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Reihe/Serie | Advances in Experimental Medicine and Biology |
Zusatzinfo | VIII, 150 p. 9 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Maße | 178 x 254 mm |
Gewicht | 490 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
Medizin / Pharmazie ► Studium | |
Schlagworte | Colorectal Cancer • EGFR • MSI • Organoids • targeted therapy |
ISBN-10 | 3-030-02770-8 / 3030027708 |
ISBN-13 | 978-3-030-02770-4 / 9783030027704 |
Zustand | Neuware |
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