Endocrine Therapy in Breast Cancer

Describes the strategies for hormone suppression and blockade in the management of breast cancer. This book explores the effects of tamoxifen, selective estrogen receptor modulators (SERMs), aromatase inhibitors, and their combination on both breast cancers and normal tissues. It is for endocrinologists; gynecologists; obstetricians; and others.

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This reference evaluates and describes the latest strategies for hormone suppression and blockade in the management of early and advanced stage breast cancer and explores the effects of tamoxifen, selective estrogen receptor modulators (SERMs), aromatase inhibitors, and their combination on both breast cancers and normal tissues.

Endocrine Therapy in Breast Cancer
details modern techniques for molecular profiling, monitoring, and targeting

offers methods to identify high-risk groups

evaluates molecular biomarkers in breast cancer assessment

examines the potential toxicity of estrogen receptor (ER)-directed endocrine therapy

investigates the development of endocrine resistance

discusses neoadjuvant and preoperative approaches in patient care

reviews mechanisms that lead to estrogen-independent phenotypes
Surveying the medical, surgical, and pathological aspects of endocrine therapy, as well as future research opportunities, Endocrine Therapy in Breast Cancer is a concise and in-depth manual for medical, surgical, and radiation oncologists; endocrinologists; gynecologists; obstetricians; pharmacologists; family physicians; reproductive biologists; epidemiologists; and medical school students.