Practical Radiobiology for Proton Therapy Planning (eBook)

Bleddyn Jones is Professor of Clinical Radiation Biology at the new Gray Institute for Radiation Oncology and Biology at the University of Oxford, as well as Honorary Consultant in Clinical Oncology, Oxford Radcliffe Hospitals NHS Trust. Over the past 20 years he has been involved with selection and referral of patients abroad for particle therapy. Present research interests include development of new accelerator technology, better prediction of the biological effects of different qualities of radiation and the role of fractionation in particle beam therapy. He is Deputy Director of the Oxford Master of Science course in Radiation Biology and Co-Director of the new Particle Therapy Cancer Research Institute. 

Preface
1. Particle physics for biological interactions

2. The essential radiobiology background

3. Some important medical and surgical
considerations, including clinical trials

4. Treatment planning and further medical perspectives

5. Historical development of radiotherapy
including what was learned from fast neutrons

6. Fractionation

7. The case for using a variable proton RBE

8. A general RBE simple efficiency model
for protons and light ions

9. 
Inclusion of the energy-efficiency LET and RBE model in proton therapy

10. Compensating for elapsed time:
unintended treatment interruptions & re-treatments

11. Errors of Bragg
Peak Positioning and their radiobiological correction

12. Additional considerations and conclusions