Genetics of Steroid Biosynthesis and Function

Buch | Hardcover

498 Seiten

2002
CRC Press (Verlag)
978-0-415-27878-2 (ISBN)

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This volume provides an accessible, up-to-date overview of modern steroid biology for both the professional and novice researcher alike.

Steroids are among the most widely prescribed drugs for humans, and steroid signaling pathways are present in vertebrates, plants, insects and fungi, presenting new avenues for biotechnological intervention. Genetics of Steroid Biosynthesis and Function focuses on the genetic and cellular aspects of mammalian steroid hormones with particular attention to inherited gene lesions. With contributions from a panel of international experts, this volume provides an accessible, up-to-date overview of modern steroid biology for both the professional and novice researcher alike.

J.I. Mason

Steroid Biosynthesis: Enzymology, Integration and Control. Sterol Biosynthesis. Vitamin D Biosynthesis and its Disorders. Bile Acid Biosynthesis. Cholesterol Metabolism in Steroidogenic Tissues. Steroid 21-Hydroxylase. Steroid 11ß-Hydroxylase Isozymes. 3ß-Hydroxysteroid Dehydrogenase/ Isomerase Deficiency. Human 17a-Hydroxylase/17, 20-Lyase. Aromatase: Insights into the Roles of Estrogens Revealed by Natural and Targeted Mutations. 17ß-Hydroxysteroid Dehydrogenase and 5a-Reductase Deficiencies. Steroid Metabolism in Peripheral Tissues. Animal Models of Impaired Steroidgenesis. Regulation of Gene Expression by the Nuclear Receptor Family. Neurosteroids and Brain Sterols.

Erscheint lt. Verlag	23.5.2002
Verlagsort	London
Sprache	englisch
Maße	174 x 246 mm
Gewicht	1080 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-415-27878-3 / 0415278783
ISBN-13	978-0-415-27878-2 / 9780415278782
Zustand	Neuware