Atlas of Allergic Diseases

Dedication.- Preface.- Section I: Immunology and Basic Science.- 1 Molecular Biology Techniques for the Investigation of Immune Activation and Immunologic Dysfunction.- 2 Immunoglobulin Structure and Function.- 3 The Complement System.- Overview of the Complement System.- Protein Components.- Regulatory Proteins.- Complement Deficiencies and Abnormalities.- 4 Chemokines and Their Receptors.- Role and Functions of Chemokines.- Disease Involvement.- Assays.- Future Therapies.- 5 Mast cell- and Basophil-derived Mediators.- Morphology.- Activation.- Functions.- Therapeutic Approaches.- 6 The Eosinophil.- Clinical Conditions with Tissue and Blood Eosinophilia.- Morphology of Eosinophils and Eosinophil Products.- Immunobiology of Eosinophils.- 7 Aerobiology and Aeroallergens.- Sampling Devices 50.- Outdoor Aeroallergens 53.- Indoor Aeroallergens 60.- 8 Immunology Laboratory Techniques.- Allergy Skin Tests.- Nonradioactive Techniques That Use Immunologic Reagents.- The Gene Array Technique.- Techniques That Use High-performance Light Sources.- Techniques to Determine Phagocyte Dysfunction.- Section II: Allergy and Clinical Immunology.- 9 Urticaria and Angioedema.- Urticaria.- Angioedema.- Classification.- Mastocytosis.- Treatment.- 10 Atopic Dermatitis.- 11 Contact Dermatitis.- 12 Allergic Eye Disorders.- Atopic Disorders of the Eye.- Nonatopic Disorders of the Eye.- Ophthalmologic Procedures in the Evaluation of Atopic Disorders of the Eye.- 13 Rhinitis.- Mechanisms.- Etiology and Epidemiology.- Diagnosis.- Examination of the Nasal Cavity.- Physical Findings.- Therapy.- 14 Sinusitis.- Anatomy.- Imaging.- Chronic Sinusitis.- Endoscopic Sinus Surgery.- Complications of Sinusitis.- Upper Respiratory and Head and Neck Infections.- 15 Allergic Bronchopulmonary Aspergillosis.- Pulmonary Infiltrates with Eosinophilia Syndrome.- Diagnosis.- Clinical Stages.- Treatment.- 16 Hypersensitivity Pneumonitis.- 17 Pulmonary Function Testing and Bronchial Provocation.- Physiologic Basis of Pulmonary Function Testing.- Spirometry in the Clinical Setting.- Bronchial Provocation Challege Testing.- Infant Pulmonary Function Tests.- 18 Allergen Immunotherapy.- Vaccines.- Mite and Insect Allergens.- Mammal Allergens.- Fire Ant and Hymenoptera Allergens.- Outdoor Allergens.- Immunologic Mechanisms.- 19 Latex Allergy.- 20 Asthma in Adults.- Epidemiology and Etiology.- Pathology and Pathogenesis.- Clinical Features and Diagnosis.- Management.- 21 Occupational Asthma.- Characteristics of Industrial Allergens and Inhalants.- Predisposing Factors.- Clinical and Pathogenic Features.- Diagnosis and Management.- 22 Food Allergy.- Clinical Manifestations of Food Hypersensitivity.- Diagnosing Adverse Food Reactions.- Management.- Prognosis.- 23 Insect Allergy.- Bites.- Systemic Allergic Reactions.- 24 Otitis Media.- Anatomy.- Classification.- Pathogenesis.- Evaluation.- Diagnosis.- Immune Evaluation.- Management.- 25 Aerosols and Inhaler Therapy.- Basic Aspects of Drug Delivery to the Lung.- Dry Powder Inhaler Delivery.- Nebulized Delivery.- Metered-dose Inhaler Delivery.- Inhalation Techniques.- 26 Immunodeficiency Disorders.- Disorders of T- and B-cell Function.- Disorders of Granulocytes and Complement.- X-linked Agammaglobulinemia.- Common Variable Immunodeficiency.- Combined Immunodeficiency and Severe Combined Immunodeficiency.- Chronic Mucocutaneous Candidiasis.- Hyper-lgE Syndrome.- Chronic Granulomatous Disease.- Leukocyte Adhesion Deficiency.- Chediak-Higashi Syndrome.- Gene Defects.- 27 Allergic Drug Reactions.- Typical Allergic Reactions to Drugs.- Antibiotic Allergy.- Drug Desensitization and Challenge Testing.- Radiocontrast Media Allergy.