Immunotherapy of Melanoma - Anand Rotte, Madhuri Bhandaru

Immunotherapy of Melanoma

Buch | Softcover
XI, 434 Seiten
2018 | 1. Softcover reprint of the original 1st ed. 2016
Springer International Publishing (Verlag)
978-3-319-83890-8 (ISBN)
213,99 inkl. MwSt
lt;p>This book focusses on the different types of immunotherapeutics that are currently being used and developed for the treatment of melanoma. In recent years, immunotherapy has revolutionized the treatment of metastatic melanoma and other types of cancer.

Discussing treatment options for melanoma and the success of immunotherapy along with the challenges of immunotherapy, this book covers epidemiology, susceptibility genes, and treatment recommendations from Society for Immunotherapy of Cancer, as well as immune based therapies such as aldesleukin, Intron-A, Sylatron, Yervoy, Opdivo, Keytruda, Imlygic, DC vaccines and adoptive cell therapy.

The detailed information included on the key immune cells involved in anti-tumor immune response and immune-inhibitory mechanisms in tumor microenvironment will aid the understanding of tumor immunology. Both academic as well as industry-based researchers, developing novel anti-cancer therapies, will also benefit from the details of promising molecular targets and immunotherapeutic strategies under investigation.

With 132 illustrations including synopsis tables for important information, over 1200 references (majority of which are openly accessible) and details of more than 150 ongoing clinical trials, this book is a valuable source of information for health care providers as well as cancer biologists interested in learning about melanoma and the significant advances made by immunotherapy. 

lt;p>Contents

Preface

1. Melanoma

            1.1 Introduction, history and epidemiology

            1.2 Diagnosis, subtypes and staging

            1.3 Etiology

            1.4 Treatment

2. Tumor immunology

            2.1 Overview of immune system

            2.2 Dendritic cells

            2.3 T-cells

            2.4 Mechanisms of immune evasion by cancer

3. Immune based drugs approved for treatment of melanoma<

            3.1 IFN- 2b

            3.2 IL-2

            3.3 Ipilimumab

            3.4 Nivolumab

            3.5 Pembrolizumab

            3.6 Talimogene laherparepvec

4. Promising immunotherapeutic approaches in clinical trials

            4.1 Introduction

            4.2 Monoclonal antibodies

            4.3 Cytokines

            4.4 Cancer vaccines

p;           4.5 Dendritic cells

            4.6 Adoptive cell therapy

5. Challenges of immunotherapy


Index

Erscheint lt. Verlag 7.7.2018
Zusatzinfo XI, 434 p. 59 illus., 52 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 916 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Studium
Schlagworte Adoptive cell therapy • cancer vaccines • Check point blockers • immunotherapy • melanoma
ISBN-10 3-319-83890-3 / 3319838903
ISBN-13 978-3-319-83890-8 / 9783319838908
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich

von Hannes Leischner

Buch | Softcover (2023)
Urban & Fischer in Elsevier (Verlag)
27,00

von Stein Husebø; Gebhard Mathis; Eva Katharina Masel

Buch | Softcover (2023)
Springer (Verlag)
49,99