Congenital Heart Diseases: The Broken Heart -

Congenital Heart Diseases: The Broken Heart

Clinical Features, Human Genetics and Molecular Pathways
Buch | Softcover
XXX, 765 Seiten
2018 | 2016
Springer Wien (Verlag)
978-3-7091-4882-2 (ISBN)
213,99 inkl. MwSt
This book provides comprehensive insights into congenital heart disease from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. It is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and related animal models and pathways. Taken together these chapters, which were written by and for clinicians and researchers, provide an integrated and cutting-edge resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.

Silke Rickert-Sperling, MD, is Professor of Cardiovascular Genetics at the Charité, Medical University Berlin and coopted professor at the Faculty of Biology, Chemistry and Pharmacy of the Free University Berlin. She leads an interdisciplinary research group at the ECRC (Cardiovascular Genetics Group). Her research focuses on elucidating the molecular mechanisms as well as genetic parameters underlying cardiac development in health and disease. She hopes to combine knowledge of molecular etiologies and mechanisms to eventually improve preventive and therapeutic opportunities for patients. Robert Kelly, PhD, is Group Leader at the Developmental Biology Institute of Marseilles - Luminy in France. His groups research focuses on the cellular and molecular processes regulating development of these progenitor cells in the mouse and their contribution to the developing heart and craniofacial skeletal muscles. Dr Driscoll is Professor of Pediatrics, Mayo Clinic College of Medicine and the Mayo Clinic, Rochester, Minnesota, USA. He is emeritus chair of the Division of Pediatric Cardiology, Mayo Clinic.

Section I: General introduction in cardiac development.- Section II: Different chapters covering the different types of congenital heart disease.- Section III: The overall perspective.

"The book describes the different pathologies comprising congenital heart disease. ... The audience is adult or pediatric cardiologists who care for patients with congenital heart disease. ... This is a great resource, especially geared for cardiologists or cardiology team members with an existing fundamental knowledge of CHD, as well as those engaged in the bench research side." (Shawn Ragbir, Doody's Book Reviews, March, 2016)

Erscheint lt. Verlag 31.3.2018
Zusatzinfo XXX, 765 p. 107 illus., 87 illus. in color.
Verlagsort Vienna
Sprache englisch
Maße 155 x 235 mm
Gewicht 1607 g
Themenwelt Medizin / Pharmazie Studium
Schlagworte cardiac malformation • Congenital Heart Disease • genomics • Heart development • molecular cardiology • Transcriptomics
ISBN-10 3-7091-4882-0 / 3709148820
ISBN-13 978-3-7091-4882-2 / 9783709148822
Zustand Neuware
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