Antibiotic Development and Resistance -

Antibiotic Development and Resistance

Buch | Hardcover
288 Seiten
2001
CRC Press (Verlag)
978-0-415-27217-9 (ISBN)
219,95 inkl. MwSt
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Ideal for those involved in the fields of medical microbiology and pharmaceutical sciences, this book provides a comprehensive review of all aspects of resistance and addresses new concepts in the field of antibiotic development.
The increasing resistance of bacteria towards all current classes of antibiotics is now a serious health problem in both developed and developing countries. Antibiotic Development and Resistance presents 15 chapters that explore the medical issues raised by this development and review the relevant literature. The book begins by reviewing the global status of bacterial infections and resistance. The chapters that follow describe the mechanisms involved, the spread of antibiotic resistance and its reversibility. An international team of authors addresses new theories and recent discoveries in bacterial resistance, including:

" The role of antibiotic efflux mechanisms in resistance
" The cost of resistance to bacteria
" The importance of low-level resistance in the early development of clinically relevant resistance

The final section of the book investigates modern techniques for the development of new drugs and highlights the importance of genomics and combinatorial chemistry in the search for new targets and antimicrobials. Ideal for clinical microbiologists, pathologists, infectious disease clinicians and researchers in medical microbiology and pharmaceutical sciences. Antibiotic Development and Resistance provides a comprehensive review of all aspects of resistance and addresses new concepts in the field of antibiotic development.

Hughes/, Diarmaid; Andersson/, Dan I

Part 1. The Clinical Context. Part 2. Mechanisms of Antibiotic Resistance. Part 3. Bacterial Genetics and Antibiotic Resistance Dissemination. Part 4. Reversibility of Antibiotic Resistance. Part 5. Development of New Antibiotics.

Erscheint lt. Verlag 11.10.2001
Verlagsort London
Sprache englisch
Maße 178 x 254 mm
Gewicht 762 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
ISBN-10 0-415-27217-3 / 0415272173
ISBN-13 978-0-415-27217-9 / 9780415272179
Zustand Neuware
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